| Objective:This study is a retrospective study,which mainly focuses on the statistical analysis of relevant clinical indicators and TCM syndromes of patients with NSTE-ACS,and studies their distribution,with the purpose of assisting the dialectical diagnosis of traditional Chinese and western medicine,so as to better guide clinical diagnosis and treatment.This paper discusses the correlation between TCM syndrome element characteristics and clinical indexes of NSTE-ACS,and provides reference for the standardized diagnosis and treatment of integrated traditional Chinese and western medicine.Methods:From September 2017 to September 2019 in tianjin nankai hospital during the period of basic clinical data of 236 patients with NSTE-ACS general,the accompanying symptoms of traditional Chinese medicine,history of disease,ECG,blood routine,biological markers and UCG results and statistics were retrospectively analyzed,and at the same time of the normal physical examination data through the comparative analysis as the control group;The clinical indicators of patients with different TCM syndromes of NSTE-ACS were compared in groups to discuss whether these clinical indicators were correlated with the diagnosis of patients with different TCM syndromes of NSTE-ACS.Results:In this study,there were a total of 236 patients with NSTE-ACS,with the highest proportion(67.80%)among those over 60 years old.The ratio of male to female is1:0.70.Among the patients with NSTE-ACS,125(52.97%)had a history of smoking,which was statistically significant compared with the control group(P<0.05).Among the previous medical histories of NSTE-ACS,148(62.71%)patients had a history of hypertension,98(41.53%)patients had type 2 diabetes,and 69(29.24%)patients had hyperlipidemia.Compared with the control group,the difference was statistically significant(P<0.05).The most common symptoms in patients with NSTE-ACS were chest tightness and pain(92.80%),shortness of breath(77.97%),dizziness(70.76%),and more common.In this study,the composite syndrome types of NSTE-ACS patients including stagnation of the heart blood(39.83%),qi deficiency and blood stasis(21.61%),phlegm heart arteries and veins(13.56%)and qi stagnation and blood stasis(9.75%)were more common.Patients with NSTE-ACS were grouped according to syndrome type,and the distribution of blood stasis(72.88%),qi deficiency(25.42%)and phlegm turbidity(13.56%)were relatively common.In this study,the heart rate of patients with NSTE-ACS at admission was calculated according to different syndrome elements,and the heart rate of patients with Yin deficiency and concurrent syndrome was higher than that of patients with non-yin deficiency,and the difference was statistically significant(P<0.05).According to the different types of co-syndromes and the non-co-syndromes group,the EF values of the hospitalized patients were collected and compared.The EF values of the patients with virtual syndromes were lower than those with non-virtual syndromes,and the difference was statistically significant(P<0.05).The activation levels of platelet membrane surface receptors(PAC-1+,CD62p+)were statistically analyzed according to the classification and grouping of different syndromes.Compared with the non-blood stasis group,the activation levels of platelet membrane surface in the blood stasis and co-syndromes group were higher,and the difference was statistically significant(P<0.05).According to the comparative analysis of the CRP values in different groups according to different syndrome types,the overall statistics showed that the CRP value of NSTE-ACS was generally higher than the normal range,and the difference was statistically significant in the classification of blood stasis and the classification of phlegm and turbidity(P<0.05).According to the classification of different syndromes in traditional Chinese medicine,the study subjects were classified and grouped.According to the statistical analysis,it was found that the PLR values of the blood stasis and co-syndromes group of NSTE-ACS patients were higher than those of the non-blood stasis group,the qi-deficiency and co-syndromes group than those of the non-qi-deficiency group,and the differences were statistically significant(P<0.05).Different syndrome types were used to classify and group the subjects.Through statistical analysis,it was found that the MPVLR values of NSTE-ACS patients with blood stasis and co-syndromes were higher than those ofnon-blood stasis group,qi stagnation and co-syndromes group than those of non-qi stagnation group,qi deficiency and co-syndromes group than those of non-qi deficiency group,and the differences were statistically significant(P<0.05).Conclusion:Among the NSTE-ACS patients in this study,the proportion of patients with blood stasis syndrome was the largest,followed by qi deficiency and phlegm turbidity.The proportion of stagnation of the heart blood in the compound syndrome type was the highest,followed by qi deficiency and blood stasis,phlegm and blood stasis,qi stagnation and blood stasis.This indicates that blood stasis and phlegm turbidity are the key pathogenesis of NSTE-ACS patients.Traditional Chinese medicine believes that phlegm and blood stasis can be converted to each other,blood stasis block,qi,blood and body fluid transport is unfavorable,can be transformed into phlegm,phlegm turbidity blocked blood,blood circulation is not free,if phlegm and blood stasis mutually stuck,normal blood flow is not free,heart and pulse block blocked,and it can cause illness generally painful.Qi can organize the movement of blood,qi deficiency,qi stagnation can cause the blood to run not free,thereby producing blood stasis,also can cause the heart to be blocked.The clinical indexes of patients with NSTE-ACS with different TCM syndromes were also different in this study.The heart rate of patients with Yin deficiency was faster than that of patients with other syndromes.The cardiac ejection fraction of patients with asthenia syndrome was low.The CRP value of patients with blood stasis and phlegm turbidity was significantly higher than that of other syndromes in statistical analysis.The activation degree of PLR,MPVLR and platelet membrane surface receptor(PAC-1,CD62p)was correlated with patients with different TCM syndromes.The activation degree of platelet membrane receptor was higher in patients with blood stasis.The PLR value of patients with blood stasis and qi deficiency was significantly increased,and the MPVLR value of blood stasis,qi stagnation and phlegm turbidity was significantly higher.These indicators,as early signs of disease,can help the TCM syndrome differentiation and treatment.Even from a certain extent,reflects the NSTE-ACS transformation between different TCM symptom and development regularity,whichfor us in the future of combine traditional Chinese and western medicine clinical provides some references for the standardization of diagnosis,and guide our clinical diagnosis and treatment and medication,under the circumstances of Chinese and western medicine as much as possible in life and health and prognosis in patients with security. |
PDF Full Text Request