Analysis Of The Correlation Between Recurrent Acute Pancreatitis And Helicobacter Pylori

Objective:To investigate the correlation between recurrent acute pancreatitis(RAP)and Helicobacter pylori(H.pylori).METHODS: A collection of 439 patients diagnosed with AP from Xinjiang Medical University from September 2018 to May 2019.Follow-up ranged from 24 months to 30 months.Among them,70 patients were diagnosed with RAP,and these 70 patients were regarded as the case group(Group A),80 medical examiners with no history of pancreatic disease in the outpatient physical examination center during the same period were selected as the control group(Group B)by random numbering method,80 cases were randomly selected from the 439 AP patients collected by random numbering method As a control group(group C).Observe and record the common risk factors of acute pancreatitis and Helicobacter pylori infection in the three groups of observation subjects.Use SPSS26.0 software to statistically analyze the collected data.First,analyze the general data,and then use the 2-test to analyze the factors.The three groups and the two groups are compared in pairs,and the statistical significance is selected(p <0.05)risk factors;Finally,multivariate logistic regression analysis was used to analyze risk factors with more independent effects,and the focus was on the relationship between Helicobacter pylori infection and RAP.Results: 40 cases of H.pylori(+)were found in 70 patients in case group C,with an infection rate of 57.14%,31 cases of H.pylori(+)were found in 80 patients in control group A,with an infection rate of38.75%,and 33 cases of H.pylori(+)were found in 80 patients in control group B,with an infection rate of 41.25%;the results of the analysis of each risk factor showed that The results of the risk factor analysis showed that gender,history of alcohol consumption,history of biliary tract disease,hypertriglyceridaemia and H.pylori infection were statistically significant(P<0.05)in relation to the occurrence of RAP.Finally,using a multifactorial logistic regression model,the results showed that H.pylori infection(OR =5.029,95% CI(2.961-17.958),history of alcohol consumption(OR=3.798,(95% CI(1.447-12.249),history of biliary tract disease(OR=3.549,(95% CI 1.496-13.832)and high triglycerides(OR=4.723,95%(CI 1.491-17.076)were statistically significant(P<0.05)with the occurrence of RAP,and the ORs were all greater than 1,suggesting that the occurrence of RAP was associated with all four factors: H.pylori infection,history of alcohol consumption,history of biliary tract disease,and high triglycerides.The results suggest that H.pylori infection significantly increases the risk of RAP.Conclusions:(1)RAP is associated with H.pylori infection,and H.pylori infection may significantly increase the incidence of RAP;(2)alcohol consumption and high triglycerides are the main risk factors in this group of RAP patients.