Study On The Correlation Between Primary Angle Closure Glaucoma And Choroidal Thickness

Objective: To investigate the association between PACG and CT.Methods: It is a retrospective study.A total of 35 patients(43 eyes)with APACG,26 patients(46 eyes)with CPACG and 46 patients(81 eyes)with normal eye condition and used as the control group in the study.EDI-OCT was used to measure and compare the foveal,nasal,temporal,superior and inferior CT of APACG,CPACG and normal control groups.The CT were labeled as subfoveal choroidal thickness(SFCT),Nasal 2 mm(N 2 mm),Temporal 2 mm(T 2 mm),Superior 2 mm(S 2 mm),Inferior 2 mm(I 2 mm).Linear regression analysis was used to explore the related factors of CT.Logistic regression analysis was used to evaluate the association between CT and presence of APACG and CPACG.Results: There was no significant difference in CT of APACG,CPACG and normal control group(P>0.05).CT of all sites were negatively correlated with axial length(AL).N 2 mm and I 2 mm were also negatively correlated with age,anterior chamber depth(ACD),SFCT was negatively correlated with age and AL(B<0,P<0.05).Multivariate logistic analysis showed that there was an association between S 2 mm and APACG(P=0.029),the odds ratio(OR)and 95% confidence interval(CI)was 0.975(0.953,0.997).There was no association between CPACG and CT at all locations(P>0.05).Conclusion: Age,AL and ACD were the factors that related to choroidal thickness.It was also confirmed that there was an association between decreased S 2 mm and APACG.However,there was no correlation between CPACG and CT at all locations.