Multi-phase 3D-ASL And SWI Imaging In The Diagnosis Of Acute Ischemic Cerebral Infarction

Objective: To explore the application value of three-dimension arterial spin labeling(3D-ASL)and susceptibility weighted imaging(SWI)in the diagnosis of acute ischemic cerebral infarction.Materials and methods: Collect 50 patients with acute ischemic cerebral infarction before treatment by conventional magnetic resonance plain scan,DWI,3D-ASL and SWI image data,according to whether there is ASL hypoperfusion area greater than DWI area,determine whether there is ischemic half Dark zone;then according to whether the hypoperfusion area on the multi-temporal3D-ASL image has cerebral gyrus-like hyperperfusion,it is divided into a hyperperfusion group and a non-hyperperfusion group.According to whether there is abnormal vein increase and thickening in the SWI lesion area,it is divided into abnormal The venous display group and the normal display group were based on the clinical NIHSS scores of patients in each group,and were used as the basis.The rank sum test was used to analyze and compare the imaging performance and prognosis of patients.P<0.05 was considered statistically significant.difference.Results:(1)Of the 50 patients,35 were male and 15 were female,with an average age of 60.22±10.61 years.DWI was found to be diffusion limited.MRA showed corresponding responsible vessel stenosis or occlusion,in which ischemic penumbra 34 For example,the detection rate was 68%.(2)Of the 50 patients,17 were in the high-perfusion group and 33 were in the non-hyperperfusion group.Among the hyperperfusion group and the non-hyperperfusion group,the imaging performance was statistically different from the prognosis.(3)Of the 50 patients,13 were in the venous abnormality display group and 37 were in the normal display group.Among them,the imaging manifestations of the venous abnormality display group and the normal display group were statistically different from the infarct size and prognosis.Conclusions:(1)It is further confirmed that when the area of ??ASL low perfusion is greater than the area of ??DWI,it can highly suggest the existence of ischemic penumbra.(2)Multi-temporal 3D-ASL imaging can reflect the situation of hyperperfusion around acute ischemic cerebral infarction.Early hyperperfusion often indicates the establishment of collateral circulation around the lesion,and the prognosis is relatively good.(3)SWI showed that the venous blood vessels in the lesion area increased and thickened,indicating that the lesion was severe ischemia and hypoxia,the infarct area was large,and the prognosis was relatively poor.(4)The combination of ASL and SWI imaging features helps to comprehensively evaluate the blood perfusion in the lesion area of ??patients with acute cerebral infarction,and the two technologies have the advantages of no contrast agent and noninvasive,real-time dynamic monitoring,etc.Patient treatment and prognosis assessment have important application value.