| Objective Traumatic brain injury（TBI）is one of the common traumatic diseases.Every year,a large amount of money is spent on the treatment of TBI,but the treatment effect of patients is not significantly improved The indicators of blood coagulation function in patients with severe head injury and Glasgow coma scale Clinical pulmonary infection score and Glasgow prognostic score collection analysis,evaluation of blood coagulation function index and value for the prognosis of patients with lung infection score,and discusses the relationship between the two,according to the results timely adjust the treatment and prevention of complications,for improving the prognosis of patients Improving survival rate and humanistic care has certain clinical significance.Methods General clinical data of 64 patients admitted to ICU after acute craniocerebral injury in our hospital from June 2019 to June 2021 were collected.Indicators of coagulation function including platelet PT APTT Glasgow coma（GCS）score and clinical pulmonary infection（CPIS）score were completed daily,and the lowest GCS score and the highest CPIS score were recorded respectively28 days later,all the enrolled patients were followed up（except death）.The prognostic data were determined by GOS score（Glasgow outcome score）and analyzed by SPSS20.0 software.The count data n（%）were analyzed by Chi-square（χ2）test,and the measurement data（x±s）were analyzed by T test.Correlation was analyzed by Pearson correlation analysis.The difference of 0.05 was statistically significant.Results The 64 TBI patients admitted to ICU included 42 with severe head injury and15 with death after 30 days.There were statistically significant differences in age,injury type,GCS score and hypotension between the survival group and the death group（P<0.05）PT value of d-dimer in patients with moderate and severe craniocerebral injury was significantly longer or higher than normal,and PT value of D-dimer in patients with severe craniocerebral injury was significantly longer or higher than that in patients with moderate and severe craniocerebral injury,and the comparison between the two groups was statistically significant（P<0.05）APTT FIB and platelet count in the two groups were approximately within the normal range,and there was no statistical significance between the two groups（P < 0.05）The CPIS score of patients with moderate severe craniocerebral injury was higher than the normal value,and the highest CPIS score of patients with severe craniocerebral injury was significantly higher than that of the moderate group,and the comparison between the two groups was statistically significant（P<0.05）The fitting curve of GCS score and CPIS score showed that CPIS score increased significantly when GCS score was less than 6-7According to the GOS score of 64 patients at 28 days after surgery,38 patients in the good prognosis group and26 patients in the poor prognosis group had statistical significance compared with the good prognosis group in terms of coagulation function indexes and CPIS score（P<0.05）In addition,clinical pulmonary infection score was positively correlated with D-dimer to a certain extent（r=0.965,P<0.05）,when the d-dimer content was higher,the CPIS score was higher.Conclusion After traumatic brain injury,patients will have abnormal coagulation function,and some indicators of coagulation function,such as PT time and D-dimer content,have certain evaluation value for the severity of TBI patients,and each coagulation function indicator has certain evaluation value for the prognosis.After traumatic brain injury,patients are prone to pulmonary infection.The severity of pulmonary infection,namely CPIS score,has certain evaluation value for the severity of injury and prognosis of TBI patients.Coagulation function,such as d-dimer content,has a certain correlation with the severity of pulmonary infection,namely CPIS score,so the combination of the two has a certain guiding and reference role in the prognosis and treatment of pulmonary infection. |
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