Effects Of Low-flow Oxygen Supply On Oxygenation Index And Cerebral Oxygen Saturation During One-lung Ventilation

Objective: To investigate the effect of low-flow oxygen supply on oxygenation index and cerebral oxygen saturation in patients undergoing thoracic surgery during one-lung ventilation under general anesthesia.Methods: Sixty patients undergoing thoracic surgery(thoracoscopic radical resection of lung cancer/esophageal cancer)were randomly divided into experimental group and control group,with 30 cases in each group.In the experimental group,during one-lung ventilation,a thin catheter was used to connect oxygen to the non-ventilated lung,and the oxygen flow rate was 1～3L/min continuously.In the control group,no treatment was given after one-lung ventilation,and the non-ventilated lung was directly connected with the atmosphere.The cerebral oxygen saturation(r Sc O2)at each point after entering the room(TO),inducing(T1),10min(T2),20min(T3),30min(T4)and 1h(T5)after one-lung ventilation were recorded during operation.arterial blood was taken at T0,T4 and T5 to measure blood gas,and t0,t4 and t5 were calculatedResults:Compared with the control group,Pa O2 and oxygenation index increased in the experimental group from T4 to T5,and the difference was statistically significant(P <0.05).Compared with the control group,the cerebral oxygen saturation in the experimental group did not increase significantly from t0 to t5,and the difference was not statistically significant(P > 0.05).Compared with TO,cerebral oxygen saturation decreased from T2 to T5,and the difference was statistically significant(P<0.05).Conclusion:Low-flow oxygen supply on non-ventilated side during one-lung ventilation can improve arterial oxygen partial pressure and oxygenation during operation,but has no obvious effect on changes of cerebral oxygen saturation.