| Objective: To study the remission of clinical symptoms and signs of clinically diagnosed patients with malignant bowel obstruction after somatostatin combined with conventional intestinal obstruction treatment,and to compare the changes of three inflammatory indexes in blood before and after the application of somatostatin,to study whether somatostatin is effective in the treatment of malignant bowel obstruction.Methods: A total of 60 patients with malignant bowel obstruction diagnosed during hospitalization in the Second Department of General Surgery of Liaoning Provincial People’s Hospital from September 2018 to December 2020 were selected as the observation objects of this study.Appeals for 60 patients diagnosed by using stochastic indicator,were randomly divided into observation group and control group 30 cases,two groups of patients in clinical treatment are regular gives the general treatment of intestinal obstruction:Abstain from water and foods,total parenteral nutrition(TPN),gastrointestinal decompression,and give gastrointestinal spasticity relievers,analgesics and other adjuvant treatments when necessary.Observation group was treated with somatostatin on the basis of conventional treatment,and both groups were treated for 1 week.The aggravation or remission of clinical symptoms and signs and the changes of WBC,C-reactive protein(CRP),procalcitonin(PCT),the peripheral blood inflammatory indicators in2 groups were compared and analyzed.Results: The total effective rate of clinical symptom relief in observation group was higher than control group after the application of somatostatin,the difference was statistically significant(P < 0.05).However,there was no statistical significance in the changes of 3 inflammatory indexes in peripheral vein blood between the two groups(P > 0.05).Conclusions: Somatostatin has a good effect in relieving the clinical symptoms of patients with malignant bowel obstruction,but has no effect on systemic inflammatory response. |
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