The Effect Of Compound Lidocaine Cream On Postoperative Pharyngeal Complications Under Different Cuff Pressures

Objective:To observe the effect of compound lidocaine cream on the incidence and severity of postoperative pharyngeal complications after tracheal intubation under different conditions of endotracheal catheter cuff pressure.Methods:In this study,A total of 140 subjects underwent elective laparoscopic gynecological surgery were randomly divided into group A,group B,group C and group D(35 cases each).Patients in group A were endotracheal tube intubated with normal tubes and maintained the cuff pressure at 30 cm H2 O.Patients in group B were endotracheal tube intubated with compound lidocaine cream and maintained the cuff pressure at 30 cmH2 O.Patients in group C were endotracheal tube intubated with normal tubes and maintained the cuff pressure at 40 cm H2 O.Patients in group D were endotracheal tube lubricated with compound lidocaine cream and maintained the cuff pressure at 40 cmH2 O.The incidence and severity of postoperative sore throat、hoarseness and cough at 2 hours,4 hours and 24 hours after extubation were recorded.SPSS22.0 statistical software was used for data analysis,and P<0.05 was statistically significant.The effects of compound lidocaine cream on postoperative pharyngeal complications in patients undergoing laparoscopic gynecological surgery under different capsular pressures were compared.Results:1.The demographic data of the four groups were not statistically significant.2.After the establishment of pneumoperitoneum and Trendelenburg position,the peak airway pressure was significantly increased in all four groups3.Two hours after extubation,the incidence of postoperative sore throat in the four groups was 28.6% 31.4% 60% and 48.6%.The incidence and severity of postoperative sore throat in high cuff pressure groups is higher and heavier than low cuff pressure groups.Compound lidocaine cream could not improve postoperative sore throat in low cuff pressure groups,but could reduce the incidence of postoperative sore throat in high cuff pressure groups.There was no statistical difference in the incidence and severity of postoperative pharyngeal pain among the four groups at 4 and 24 hours after extubation.4.There was no significant difference in the incidence and severity of postoperative hoarseness and cough among the four groups.Conclusions:1.The local use of compound lidocaine cream can reduce the incidence of postoperative sore throat after two hours extubation at high cuff pressure,but it has no obvious improvement effect at low cuff pressure.2.Lower endotracheal tube cuff pressure can reduce the incidence and severity of postoperative sore throat 2 hours after extubation.3.The local application of compound lidocaine cream to endotracheal catheter sheath had no significant effect on postoperative hoarse and cough under different capsular pressures.