Analysis Of Risk Factors For Atrophic Cholecystitis

Objectvie: Study the risk factors of atrophic cholecystitis and analyze the independent risk factors,provide guidance for the preoperative evaluation and intraoperative diagnosis of patients with atrophic cholecystitis,reduce the missed diagnosis rate of atrophic cholecystitis,and further improve the prognosis of gallbladder cancer.Methods: Through retrospective analysis of patients with gallbladder and cholecystitis undergoing operations in the headquarters and southern district of from July 2017 to July 2020,the patients were diagnosed as atrophy in strict accordance with the screening criteria,and through intraoperative exploration and postoperative pathology.Patients with cholecystitis were taken as the study group,with a total of 45 cases,and patients with non-atrophic cholecystitis who were clearly diagnosed by intraoperative exploration and postoperative pathology were taken as the control group.Read carefully,enroll eligible patients and remove non-eligible patients,and record in detail the basic information of the patient’s hospitalization and related data of intraoperative diagnosis and anatomical indicators.Refer to the "Chinese Chronic Cholecystitis,Gallbladder Stone Consensus(2018)".For the cases that met the selection criteria,a single factor analysis method was used to analyze the patient’s gender,patient’s age,illness time,weight,diabetes,BMI,number of right upper abdominal pain,and number of stones.Use SPSS21.0 software for statistical analysis,use T test for measurement data,and X2 test for count data.We perform further Logistic multivariate regression analysis for statistically significant risk factors,and obtain atrophic gallbladder through statistical analysis The risk factors of inflammation are analyzed by multi-factor analysis of the risk factors obtained,and the independent risk factors related to gallbladder atrophy are analyzed.Results: The collected 45 patients with atrophic cholecystitis included 35 cases of gallbladder length less than 45 mmcm with gallbladder wall atrophy and hardening,and10 cases of gallbladder volume reduction accompanied by gallbladder wall atrophy and hardening.Among the 315 patients with non-atrophic cholecystitis,313 had gallbladder stones with cholecystitis,and 2 had non-atrophic cholecystitis.A univariate analysis of the patient’s gender,age,duration of illness,weight,diabetes,BMI(body mass index),number of pain in the right upper abdomen,and number of stones,results suggesting diabetes,age,duration of illness,BMI,and number of pain in the right upper abdomen The number of stones and stones are risk factors for the formation of atrophic cholecystitis(P<0.05),and the difference is statistically significant.The risk factors derived from the analysis of atrophic cholecystitis were further analyzed by logistics multi-factor analysis,and the final result was the patient’s: age of illness(OR=2.048,P=0.044),time of illness(OR=2.431,P=0.018))And the number of stones(OR=2.859,P=0.038)are statistically significant,suggesting that it is an independent risk factor for the formation of atrophic cholecystitis in conclusionConclusion: Atrophic cholecystitis has multiple risk factors that work together,and multiple risk factors interact with each other.The preoperative diagnosis rate of atrophic cholecystitis is low.Through this study,we found that it is mainly seen in elderly patients with long gallbladder stones and cholecystitis Patients with history and multiple stones in the gallbladder.We should be more careful during intraoperative exploration and surgical operations to avoid bile duct injury.For patients with atrophic cholecystitis,we should recommend immediate surgical treatment to avoid delaying the development of gallbladder cancer.At the same time,we recommend that we should promote a reasonable diet,strengthen exercise,and avoid overweight.