Clinical Investigate Of Double Lumen Catheter With Polyester Sleeve And Its Application For The Treatment Of Chronic Joint Infection

Background:With the improvement of medical technology,the proportion of joint replacement infection has decreased to less than 5%.Currently,the number of patients receiving joint replacement surgery is gradually increasing,so the number of patients with primary joint infection and infection after joint replacement surgery will also be extremely large,and the number of patients receiving revision of infection after joint replacement surgery will also gradually increase.At present,most of the treatment schemes for joint infection are by stages,that is,the first stage is the treatment of intra-articular infection,and the second stage is the revision of the joint to restore joint fuction.Currently,there are many treatment schemes for the first stage of infection but the effective rate is poor,and the quantitative antibiotics in the joint cavity can only complete the bactericidal and bacteriostatic function in a short term.Is an effective method for the new discovery,but the joint cavity powder treatment time is still less than the built-in antibiotics,antibiotic bone cement in articular cavity antiseptic bacteriostasis in has been because of its release time and release a quantity to instability and controversial,continuous flushing tend to complicate the infection due to complicated with fungal infection,articular cavity puncture injection intermittently antimicrobials is regarded as traditional anti-infection treatment,but the repeated puncture is also a risk of concurrent joint,the local administration of foreign scholars use long pipe treatment of joint infection,prove the feasibility of indwelling catheter intermittent injection drug treatment.ObjectiveTo try to apply a double-lumen catheter with polyester sleeve for the treatment of joint infection,to carry out local injection,and to study its feasibility,effect and advantages in the treatment of joint infection.MethodsThe information of patients admitted between 2018 and 2020 for joint infection was collected,and the diagnosis of patients with non-acute stage of joint infection,or the diagnosis of patients with non-acute stage of joint infection after joint replacement surgery,generally took longer than 3 months for symptoms such as knee swelling and pain.Meets the requirements of the patients with phase 1 of the antibiotic bone cement kuang buy surgery and postoperative patients in control group by intravenous antibiotics,only conform to the requirements of the patients with 1 antibiotic bone cement kuang buy surgery and postoperative patients by double lumen catheter use of antibiotics only,into the observation group,control group 15 cases and 9 cases of observation group a total of 24 cases.Two groups of patients were accepted conventional perioperative management,because of the standard are joint infection in patients with the acute phase,no joint replacement patients are characterized by knee joint cartilage damage,can’t display function,so the intraoperative adopt removal of articular cartilage,get rid of the prosthetic replacement patients after,vancomycin use contains 0.5 g of antibiotics and create a simple spacer or femoral head,bone cement in the joints.Postoperatively,the control group received intravenous antibiotic therapy,and the observation group received transcatheter injection of antibiotic solution or suspension into the articular cavity.The data of red blood cell values,white blood cell values,recurrence rate after the first operation,number of operations required to cure joint infection,cumulative duration of intravenous medication and other data before and after surgery were collected for statistical analysis in the two groups.ResultsThe observation group and control group of c-reactive protein(CRP)as a line chart,visible observation group in the postoperative decline faster than the control group,and the earlier than the control group back to normal range,the observation group and control group of erythrocyte sedimentation rate(ESR)as a line chart,visible gap index of two groups of patients with the pace of decline after surgery is not big,but only the experimental group to restore to the normal range.SPSS 21.0 was used to analyze the recurrence of the two groups after the first open placement.The results showed that the first postoperative recurrence rate of the treatment plan in the observation group was lower than that in the control group(P=0.019),the number of operations required for joint infection cure was statistically analyzed(P=0.003),the number of operations in the observation group was less than that in the control group,and the cumulative intravenous drug application time was statistically analyzed,the results showed that the treatment time in the observation group was less than that in the control group(P=0.002).ConclusionIntermittent local injection of liquid to the infected joint with a double-lumen catheter with polyester cuff can promote the treatment of joint infection.