Application Value Of CT Energy Spectrum Imaging In The Differential Diagnosis Of Benign And Malignant Thyroid Nodules Of 1-4cm

Objective Exploring the application value and diagnostic efficacy of CT energy spectrum imaging in the differential diagnosis of 1-4 cm thyroid nodules.Methods A total of 60 patients with single thyroid nodule were involved in from Jan.2019 to Dec.2019 in our hospital who found the thyroid nodule by ultrasonic examination or self-conscious physical examination and had the postoperative pathological diagnosis after examined by CT energy spectrum imaging.In order to analyze the diagnostic efficacy of energy spectrum CT multi-parameter imaging for thyroid nodules,and to explore the diagnostic value of CT energy spectrum imaging in judging the nature of 1-4cm thyroid nodules,we performed a plain GSI scan and enhanced scan of the neck of the patient,measured the iodine concentration of the nodular lesion during the plain scan,arterial phase and venous phase,and calculated the attenuation slope of the energy spectrum curve.Consistency test was used for the diagnosis data of the two physicians,the correlation coefficient(ICC)was used for the data within the group,the t test for the independent sample was used for the measurement data,and the chi-square test was used for the comparison between the count data.Clinical diagnostic efficacy was evaluated by receiver operating characteristic(ROC)curve.Results1.CT energy spectrum imaging diagnosed 34 cases of benign nodules and 26 cases of malignant nodules;In the end,38 cases of benign nodules and 22 cases of malignant nodules were confirmed by pathological examination.2.The iodine concentration of patients in the benign group was significantly higher than that in the malignant group no matter in the plain scan phase,arterial phase and venous phase(P<0.05).The slope of the energy spectrum attenuation curve in the benign group was statistically decreased compared with that in the malignant group regardless of the plain scan phase,arterial phase and venous phase(P<0.05).There was no significant difference in capsule,calcification and border between two benign and malignant groups(P >0.05).3.It was statistically significant that the sensitivity of CT energy spectrum imaging to determine the nature of thyroid nodules was 90.91%,the specificity was 84.21%,the accuracy rate was 86.67%,and the area under the ROC curve(AUC)was 0.937Conclusions1.CT energy spectrum imaging could comprehensively determine the benign and malignancy of thyroid nodules through multiple parameters such as iodine concentration and the slope of the energy spectrum attenuation curve..2.CT energy spectrum imaging had a high sensitivity,specificity and accuracy for the diagnosis of benign and malignant thyroid nodules,which had certain guiding significance for the clinical formulation of surgery,diagnosis and treatment plans.3.CT energy spectrum imaging should be applied in clinical screening for its rapidity and non-invasion in thyroid nodules diagnosis.