Design,Implement And Application Of Development Platform For Triple Quadrupole Mass Spectrometer

Mass spectrometry is a commonly used chemical substance detection method,that is,using a mass spectrometer to measure the ion mass to obtain information such as the elemental composition and molecular structure of the sample.The mass spectrometry analysis process usually includes: ionizing the compound into ions,determining the charge-to-mass ratio of the ions,and analyzing the spectrum.A mass spectrometer usually includes three parts: ion source,mass analyzer,and detector.The most important feature of the triple quadrupole mass spectrometer is that its mass analyzer consists of a three-stage quadrupole structure.The triple quadrupole mass spectrometer has the advantages of high sensitivity and accurate quantification compared with other mass spectrometers.However,compared with single quadrupole,triple quadrupole mass spectrometer has multiple working modes and more complex working timing.In order to study the control logic and working timing of the instrument,and to research the key components of the instrument,based on virtual instrument technology,a set of development platform of triple quadrupole mass spectrometer with high modularity and strong expandability was built.The hardware part of the platform is composed of industrial control computer,PXIe board and auxiliary circuits.The software is based on the LabVIEW development environment,with state machine as the basic architecture.It was combined with two modules of instrument control and data processing.The control module is based on LabVIEW’s VISA and DAQ modules and implements control automation.The data processing part integrates the advantage of LabVIEW’s graphic interface and MATLAB’s powerful wavelet analysis algorithm package,and is adapted to the spectrum analysis algorithm,which can provide data support for instrument developers.The development platform is used to complete the control and monitoring of each part of the instrument.A MATLAB algorithm package is developed based on continuous wavelet transform and Gaussian fitting,which provides convenient mathematical analysis for instrument developers.Using the platform,the response time of ion optical parts,high voltage and quadrupole power supply were tested,the key parameters such as settling time was obtained,the timing characteristics under different working modes were tested,and the anti-crosstalk performance of the instrument was evaluated.At last,a series of test for the self-built vacuum system was completed.At present,the development platform is basically completed and can undertake the work of control instrument units,spectrogram analysis of standard products,and parts replacement experiments.At the end of this article,A plan was proposed for further improvement and update of this development platform.