Research On The Preparation And Performance Of Anti-bioadhesion Surface For Medical Devices

Surgical medical instruments are frequently used and are susceptible to abrasion.At the same time,body fluids and some drugs will also corrode medical instruments during use.These reasons cause medical devices to be scrapped ahead of schedule,cause a lot of losses and waste.The wear surface of medical equipment is easy to contain dirt,and the adhesion of bacteria and human tissues is easy to form a biofilm that is difficult to remove,which brings great difficulties to the disinfection and sterilization work.Constructing a super-hydrophobic surface on medical equipment can reduce the adhesion of body fluids,cleaning agents,disinfectants and other pollutants,making the surface less susceptible to corrosion and extending the life of the equipment;can reduce the adhesion of bacteria,which reduces the probability of infection;can also reduce blood adhesion and make it difficult for thrombosis to occur.In summary,the preparation of superhydrophobic surfaces with anti-bioadhesion ability on the surface of medical devices has great research significance and broad application prospects.In this study,a nanosecond fiber laser was used to prepare some stainless steel surfaces with a large number of pit lattices,and then it was naturally converted into a super-hydrophobic surface in the air,and its transformation mechanism was studied.Simultaneously,the method of simulation analysis was used to explore the influence of texture patterns on hydrophobic properties.In order to further improve the surface anti-bioadhesion performance,the surface was also surface modified,and then the bioadhesion test was carried out on it.The main research is as follows:(1)Some super-hydrophobic surfaces were prepared on the surface of 3Cr13 stainless steel using laser texturing.By changing the number of laser processing and the texture pattern,hydrophobic surfaces with different contact angles and rolling angles can be obtained.Changing the number of laser processing can change the surface roughness of the surface and affect the hydrophobic performance;while the texture pattern determines the solid-liquid contact ratio of the contact surface and the continuity of the contact surface,thereby affecting the hydrophobic performance.(2)The surface of the laser processed sample will be spontaneously transformed from superhydrophilic to super-hydrophobic after being placed in the air for a period of time.Using EDS and XPS to analyze the chemical composition of the surface before and after the transformation,the results show that the change of the surface chemical composition is the main reason for the hydrophobic transformation.(3)Through the method of fluid simulation analysis,the geometric model of the surface with different texture patterns is established,and the fluid calculation analysis is performed on the surface.The calculation results are consistent with the experimental results,and the experimental results are verified;and it is confirmed that the continuity of the contact surface will affect the size of the rolling angle.(4)The prepared surface is subjected to blood adhesion test and bacterial adhesion test,and the test results show that the hydrophobic surface has a good anti-bioadhesion effect.