| Mixer is a commonly used mixing instrument in medical and biological laboratories.Experiments such as enzyme reaction,cell separation and PCR reaction system require more and more mixers.Stable mixing amplitude,precise mixing speed control and temperature control are the core functions of the mixer.In this paper,a precise constant temperature homogenizer which can be used in medical and biological laboratories is designed.Combined with virtual prototype technology,from 3D modeling to static and dynamic analysis,and finally to the construction and performance test of test prototype,a complete set of R&D process is practiced,which has strong practical engineering significance.The main contents are as follows:(1)According to this subject,the parameter requirements of constant temperature mixer are calculated and designed,the transmission structure scheme and temperature control part of mixer are analyzed and selected,the dynamic balance of transmission system is analyzed,and the bearing,driving motor and temperature control part are calculated and selected.(2)Parametric assembly design(TOP-DOWN design)of constant temperature mixer is carried out by Creo 3D modeling software,and the relationship between main design variables is established.By using top-down design idea,the notebook(layout)design to skeleton model design in Creo,and finally to the design of each part.(3)Static analysis is carried out on the eccentric shaft of the mixer by ANSYS Workbench,and boundary conditions are applied to simulate the actual stress situation.The influence of design variables on the output results is studied by response surface and sensitivity analysis.Taking the minimum value of mass,deformation and equivalent stress as optimization objectives,genetic algorithm is used to optimize the eccentric shaft with multi-objective dimensions,which effectively improves the mechanical properties of the eccentric shaft.Modal analysis was carried out on the shell of the homogenizer,and it was found that the first four modal frequencies were too close to the highest speed frequency of the motor.The shell structure was optimized to improve the first modal frequency and avoid resonance.(4)Adams simulation software is used to analyze the dynamics of the transmission system of the homogenizer.Based on the parametric model of the homogenizer,four dynamic performance parameters(acceleration,speed,vibration frequency,vibration displacement)of the transmission system of the homogenizer under different working conditions are obtained by simulation calculation.Through analyzing and evaluating the performance of the transmission structure,it is found that it meets the design requirements.(5)Two experimental platforms(dynamic performance test and blending effect test)are designed and built,which verify the correctness of the simulation model and ensure that the blender can meet the design requirements during operation. |