The Design Of The Iron Group Element Catalytic Systems And Their Applications In Alkene Reactions

Through the rational design of iron element-enabled catalytic systems,we have realized the NiH-catalyzed asymmetric hydroamination of α,β-unsaturated amides,asymmetric remote hydroarylation of alkenes,and heterogeneous magnetic Se/Fe/PCN-catalyzed oxidative cracking of olefins in oxygen.In the fist part,we reported a NiH-catalyzed asymmetric hydroamination process of α,β-unsaturated amides under mild reaction conditions.Nitroarenes and hydroxylamine derivatives could be used as electrophilic amination reagents to produce the desired arylamine and alkyl amine products in moderate to high yields with excellent enantioselectivies.In the second part,we reported a NiH-catalyzed asymmetric remote hydroarylation of alkenes using a ligand relay catalysis strategy.It’s challenging to design a single chiral ligand which could well-promote both chain-walking and asymmetric coupling.By synergystic combination of a chian-walking ligand and an asymmetric arylation ligand,a wide variety of 1.1-diaryl alkanes were obtained through this formal asymmetric C（sp3）-H arylation process with excellent levels of regio-and enantioselectivities.In the third part,we prepared heterogeneous magnetic Se/Fe/PCN catalyst,which could catalyze the oxidative cracking reactions of alkenes using molecular oxygen as the cheap,mild and safe oxidant.The catalyst could be magnetically recycled and reused for multiple times,and it worked as excellent as the homogeneous catalysts.