Synthesis And Recognition Performance Of Multilocus Receptors Based On Acylhydrazone

Anion and cation are closely related to human life,but too much or too little ions will have a variety of effects on organisms,and excessive amount of heavy metal ions will not only seriously harm the environment,but also affect human health via enriching.Therefore,design simple structure,easy to synthesize,convenient and fast fluorescence chemical sensor to detect metal ions is of great significance to human life.Acylhydrazone compounds possess O=C-NH-N=R mechanism units and strong coordination ability with metal ions,which are widely used in the field of ions probe.Based on these,three multi-locus receptors based on acylhydrazone were designed and synthesized in this paper,and studied their metal ion recognition performance.This paper mainly elaborates from the following four parts:Chapter one IntroductionThis chapter introduces the basic concepts of supramolecular research background of supramolecular chemistry,the mechanism and significance of ion recognition in supramolecular chemistry,especially the significance of cation recognition in production and life.And introduces the research progress of acylhydrazone chemical sensors for different ions recognition in detail.Chapter two Synthesis and Research on recognitions and properties of Rhodamine hydrazone derivative sensor Hg²⁺and its applicationIn this chapter,a colorimetric fluorescence two-channel chemical sensor G1 with simple structure of rhodamine hydrazone was designed and synthesized for the detection of Hg²⁺in aqueous solution.The addition of Hg²⁺to DMSO/H₂O（2:8,v/v）solution containing G1changed the color from colorless to a distinct rose red,and the fluorescence changed from colorless to bright orange under ultraviolet light.The limit of fluorescence detection of G1 to Hg²⁺was as low as 6.09×10^-7 mol/L.Job’method showed that the complexation ratio of G1and Hg²⁺was 1:1.G1 is reversible in the recognition of Hg²⁺and can be used repeatedly.In addition,a quick test paper based on G1 was prepared.G1 can also qualitatively detect Hg²⁺in tap water.Chapter three Synthesis and Research on recognitions and properties of M-benzoyl hydrazone derivative sensor Cu²⁺and its applicationIn this chapter,we design and synthesize a two-channel sensor G2 based on m-dimethylhydrazone derivative,which can selectively recognize Cu²⁺through two channels over a wide p H range.The detection limit of G2 response to Cu²⁺fluorescence was as low as5.65×10^-7mol/L.Job’method showed that the complexation ratio of G2 to Cu²⁺was 1:2.G2 is reversible in the recognition of Cu²⁺and can be used repeatedly.In addition,a quick test paper based on G2 was prepared.Chapter four Synthesis and Research on recognitions and properties of M-benzoyl hydrazone derivative sensor Hg²⁺and its applicationIn this chapter,we design and synthesize a novel Hg²⁺sensor G3 based on m-m-dimethylhydrazone derivative.Research the recognition performance of G3 to metal ions by ultraviolet spectrum and fluorescence spectrum.In the DMSO/H₂O（1:1,v/v）solution,it can only sense Hg²⁺by ultraviolet and fluorescence dual channel without affected by the interference of other cations,which makes the G3 solution from colorless to light yellow color,and the yellow-green fluorescence quenching of the G3 solution.Job’method showed that the complexation of G3 and Hg²⁺ratio of 2:1.The minimum fluorescence detection limit of G3 for Hg²⁺was 3.78×10^-7 mol/L,which was lower than the maximum allowable limit of mercury ions in drinking water set by the World Health Organization（WHO）,which was6×10^-6mol/L.It is worth mentioning that G3 can be applied to the detection of Hg²⁺in water,realizing the real-time monitoring in the environment.