Design Synthesis And Performance Research Of BODIPY Derivatives With Hydrogen Chloride Gas Response Behavior

As a major industrial by-product,hydrogen chloride is widely used in chemical production.It is volatile,highly toxic,and corrosive.Long-term exposure to an environment where the concentration of hydrogen chloride exceeds the standard has a huge impact on human health,environmental pollution,instrument corrosion,storage and production safety.Traditional hydrogen chloride detection methods include chromatography-mass spectrometry detection,electrochemical detection,photochemical detection and other methods.These detection methods have a series of problems such as slow response speed,insufficient sensitivity,and inconvenience to carry.It can’t adapt to current detector requirements.Different from traditional detection methods,among many hydrogen chloride monitoring methods,photochemical methods show unparalleled superiority in terms of sensitivity,intuitiveness,operation flow,and production of sensor devices.The photochemical detection method can even get rid of the limitation of the "photometer" to realize real-time,rapid detection and judgment of the naked eye.Based on the above reasons,people have been committed to the development of sensitive hydrogen chloride photochemical sensing materials.Fluorescent probes have unparalleled advantages in sensitivity,operability and selectivity,and perform well in many fields.As the star molecule in the fluorescence family,BODIPY dye has the advantages of high sensitivity,good selectivity,high fluorescence quantum yield,high molar absorption coefficient,good light stability,narrow fluorescence spectrum peak width,and pH insensitivity.In this paper,using BODIPY dye as a fluorescent response group,a hydrogen chloride fluorescent response probe with a C=N double bond structure containing a hydrogen chloride recognition function,a pyridine unit and a triazole unit was designed and synthesized.1H-NMR was used to characterize a series of synthesized intermediates and target compounds.Using ultraviolet spectroscopy,fluorescence spectroscopy and other means to study the photochemical properties of the target product,it was found that compounds A and B can be used as a fluorescent probe for hydrogen chloride in a specific concentration range,and probe C basically has no response to hydrogen chloride.The theoretical calculation method was used to explain and explain the fluorescence response behavior of the probe,and a novel hydrogen chloride probe molecule was designed.The fluorescence response of the probe D to the hydrogen chloride molecule was predicted by calculating the frontier molecular orbital,orbital energy level distribution,ultraviolet absorption spectrum.