The Principle Study Of Non-invasive Blood Glucose Concentration Monitoring With Microwave

Blood glucose monitoring is a regular project in human physical examination.Blood glucose levels monitoring in healthy people can help screen early diabetes patients.However,diabetics need to test their blood glucose concentration several times every day.At present,the clinical blood glucose monitoring methods mostly used invasive measurement methods,which advantage is highly accuracy.In recent years,the non-invasive blood glucose monitoring methods have been extensively studied.Compared with traditional method,non-invasive blood glucose monitoring method has the advantage in no need to draw blood in the monitoring process and painless.Non-invasive monitoring methods avoid the problem of infection during monitoring process,and satisfy the needs of diabetic patients who need to test blood glucose level every day.The measurement target tissue of the blood glucose concentration monitoring method used herein is the human earlobes.The human earlobe tissue is completely exposed to the outside of the human body for easy measurement.The human earlobe tissue has the simple structure without bones,and is composed only of fat tissue wrapped with capillaries,which avoids the influence of human bones on the reflection of electromagnetic waves during the detection process.This paper raises a non-invasive blood glucose monitoring method based on low-frequency sine signals,which monitoring the blood glucose level of tested tissue by analyzing the time-frequency domain characteristic of received signals.In this paper,the electromagnetic simulation is completed based on the FDTD algorithm.The simulation of monitoring human blood glucose level using sine signals is completed by Matlab platform,and provides the theoretical result.A simulation experiment of monitoring human blood glucose concentration was performed in the laboratory.The correctness and regularity of this method are verified by the time-domain waveform,spectrum and energy density spectrum of the received signals.The variation of the received signal with the blood glucose concentration level is given from three dimensions,and the feasibility of the method was proved.The experimental results show that after the signal transfer through the earlobe model,the received signal can clearly show the difference in blood glucose concentration and change with the variation of blood glucose concentration.In this experiment,a glucose solution with a concentration of 0 to 500 mg/ dl was used as a test sample.While the concentration rises from 0 mg/ dl to 100 mg/ dl and the other experimental conditions remain unchanged,the amplitude of the signal drops by 4.5 mV,the spectrum amplitude of the received signal drops by 25%,and the amplitude of the energy density spectrum of the signal drops by 43%.When the concentration of glucose solution increased from 100 mg/ dl to 500 mg/ dl,the amplitude of the time domain signal decreased by 0.95 mV for each increase of 100 mg/ dl,the spectral amplitude of the signal decreased by 6%,and the energy spectrum amplitude has dropped by 6%.The wavelet transform is used to de-noise to improve the accuracy of the measurement results.