he goal of Total Parenteral Nutrition (TPN) is to provide protein and non-protein energy in order to promote nitrogen retention and meet energy requirements. Controversy exists on whether glucose or lipid is the optimal source of non-protein energy. A randomized clinical trial was conducted for one week to compare the effects of TPN providing 34% of non-protein energy as lipid (Group 1; n = 7) to those of hypertonic glucose TPN (Group 2; n = 6). Indices of nitrogen retention, metabolic abnormalities, physiologic stress, and fat clearance were measured. The energy and protein intakes of Group 1 exceeded those of Group 2 from days 0 to 7 (p... |