| he use of representative in vitro models has been favoured for the study of biologic and pharmacologic responses of the equine superficial digital flexor tendon (SDFT). The objectives of this study were to determine the effects of exogenous sodium hyaluronate (NaHA) and polysulfated glycosaminoglycan (PSGAG) on extracellular matrix (ECM) synthesis and cell proliferation by explants of the equine SDFT, and to compare the effects of NaHA and PSGAG at equivalent concentrations. Explants of the tensile SDFT were cultured in RPMI 1640/10% DHS/100 ;NaHA was evaluated at concentrations of 0 to 2000... |
