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Factors influencing the incidence and severity of oral mucositis in patients undergoing autologous stem cell transplantation

Posted on:2005-03-07Degree:M.SType:Thesis
University:D'Youville CollegeCandidate:Salvador, Prisco TFull Text:PDF
GTID:2454390008991030Subject:Health Sciences
Abstract/Summary:
This retrospective descriptive study documented the frequency of oral mucositis and examined the effects of certain variables in the development of oral mucositis in autologous stem cell transplants. Oral mucositis occurred in 90% of the patients, but 53.57% developed ulcerations. On average, oral mucositis started on day 7 which lasted for 6 days and resolved on day 13 after the initiation of chemotherapy. Sodium bicarbonate and mucositis mouthwashes were commonly used interventions; 72.92% of the interventions were used as secondary prevention. Oral mucositis was significantly associated with diagnosis (lymphoma), chemotherapy (etoposide and melphalan), and level of prevention (secondary). Diagnosis (lymphoma), chemotherapy (etoposide and melphalan), serum creatinine (peak level), and level of prevention (secondary) were independent predictors of oral mucositis.
Keywords/Search Tags:Oral mucositis, Autologous stem cell
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