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Analytical solutions for sensitivity contribution in nuclear imaging

Posted on:2014-03-01Degree:M.SType:Thesis
University:California State University, FresnoCandidate:DiPirro, Joseph ChristopherFull Text:PDF
GTID:2454390008955736Subject:Physics
Abstract/Summary:
The use of slit-slat collimation in diagnostic medical nuclear imaging is analyzed for the purpose of finding background sensitivity. A general derivation of sensitivity contribution is expressed for various camera positions outside particular radioactive objects. These objects can represent possible human or animal organs for different clinical imaging tasks. Rectangular, circular, elliptical, and parabolic cross-sections are analyzed for a given set of variables to represent the total background contribution within any particular shape for any given detector location, whether it is a point, line, or area sensitivity contribution.;The sensitivity of a point source is calculated for any location inside the slit-slat's field-of-view as a function of the following constraints: (i) object shape, (ii) slit distance, (iii) depth within the object, (iv) acceptance angle, and if necessary (v) attenuation coefficient of the medium, and (vi) lateral displacement of the detector. The analysis is split into parts for all shapes to find the line or area contribution within an object. The sum of the point sources can be performed digitally to find a solution in terms of the provided situation; in some cases, an exact solution was found. The line sensitivity contributions can be applied to slit-slat cameras to reduce noise and fluctuation in imaging system design and analysis.
Keywords/Search Tags:Sensitivity, Imaging
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