Computer-aided detection of periapical radiolucencies

Purpose. To methodically assess the reliability and accuracy of the Logicon Caries Detector(TM) (LCD) software in its "off-label" ability to detect the apical foramen and periapical pathology on digital radiographs, and also to determine if the software could detect experimentally produced periapical bony lesions in a dry human mandible.; Methods. 23 periapical radiographic images collected for endodontic therapy were evaluated. 4 periapical radiographs were taken of 12 experimentally produced periapical lesions in one dry human mandible. A total of 3 methods of detection were used.; Results. Applying the LCD software to preexisting radiographs showed 7 of 23 (30%) apical foramens were highlighted using the v-tool. 9 of 23 (39%) using manual method #1. 9 of 23 (39%) using manual method #2. 11 of 13 (85%) periapical radiolucency borders using the v-tool. 8 of 13 (62%) using manual method #1. 8 of 13 (62%) using manual method #2. Using a 3-angle approach 34 of 39 (87%).; Applying the LCD software to the digital radiographs of the dry human mandible 10 of 12 (83%) periapical radiolucency borders were outlined using the v-tool.; Conclusion. Using the weighted chi-square no statistically significant difference was observed between any of the methods used. Although this study found no statistical significance amongst the utility of the 3 methods, the future of this type of technology might be very significant if adapted to periapical tissue.