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The synthesis of precursors towards a Pin1-activatable gadolinium(III) MRI contrast agent

Posted on:2009-05-13Degree:M.SType:Thesis
University:Georgetown UniversityCandidate:Cho, Joseph HFull Text:PDF
GTID:2444390002998567Subject:Inorganic Chemistry
Abstract/Summary:
As the disciplines of biology and chemistry continue to converge, the need for new methods of visualizing biological phenomenon at sub-cellular and molecular levels continues to increase. To this end, molecular imaging has emerged as a multidisciplinary field that incorporates technologies, techniques and basic science from an array of sources with the goal of visualizing, characterizing and quantifying biological process in vivo at the cellular and sub-cellular levels. Spearheading the development of molecular imaging is modern medicine which has much to gain from these new insights. Molecular imaging has already played a key role in the diagnosis, prognosis, and treatment of various cancers. In vivo molecular imaging will continue to influence developments in medicine as new methods of imaging further expand the scope of biological observation and understanding.
Keywords/Search Tags:New, Biological, Imaging
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