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Evaluation of the AmpFlSTRRTM MiniFiler(TM) typing Kit: Mixture and non-probative studies

Posted on:2010-11-10Degree:M.SType:Thesis
University:University of North Texas Health Science Center at Fort WorthCandidate:Feller, Elizabeth AFull Text:PDF
GTID:2444390002480617Subject:Anthropology
Abstract/Summary:
This project was aimed to assemble and assess data from internal validations of AmpFlSTRRTM MiniFiler(TM) PCR Amplification Kit by forensic laboratories across the United States. After compilation, data was evaluated for quality of testing, results, and concordance within and between participating laboratories. It was concluded that MiniFiler(TM) can successfully amplify DNA from multiple sources in mixtures of neat and degraded samples, as well as enhance DNA profiles obtained for several types of samples with suspected PCR inhibition or degradation. The data was collected into a final report with discussions and conclusions to the findings for submission to the National DNA Indexing System (NDIS) Approval Board for authorization to use forensic DNA genotypes generated using MiniFiler(TM) in national DNA databases.
Keywords/Search Tags:Minifiler, DNA, Data
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