1-Benzotriazolyl-2-propynones as novel 1,3-biselectrophiles, benzotriazole-assisted thioacylation and synthesis of energetic materials

New synthetic strategies for the synthesis of several target molecules are the theme of this work. 1-Benzotriazolyl-2-propynones were shown to be novel 1,3-bis-electrophilic synthons. These synthons provided a new route in the synthesis of pyrido[1,2a]pyrimidin-2-ones, 2 H-quinolizin-2-ones, pyrido[1,2-a]quinolin-3-ones, and thiazolo[3,2-a]pyrimidin-7-ones. These new 1,3-bis-electrophilic synthons were compared with previous 1,3-bis-electrophilic methodologies from the literature and expanded on the role of these synthons by novel synthesis of new heterocyclic systems.; Aliphatic and aromatic thiocarbonyl-1H-6-nitrobenzotriazoles were synthesized (Chapter 3) as novel thioacylating reagents. To show their synthetic utility, these thiocarbonyl-1H-6-nitrobenzotriazoles were reacted with an alcohol to form the corresponding thionoesters.; Chapter 4 summarizes the work accomplished in collaboration with the US Army on the reasonable synthesis and characterization of broadly defined energetic materials.