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Chemical synthesis of two repeat units corresponding to the backbone of the pectic polysaccharide Rhamnogalacturonan I

Posted on:2008-12-19Degree:M.ScType:Thesis
University:University of Northern British Columbia (Canada)Candidate:Reiffarth, DominicFull Text:PDF
GTID:2441390005967900Subject:Chemistry
Abstract/Summary:
A tetrasaccharide sequence of Rhamnogalacturonan I has been synthesized starting from commercially available D-galacturonic acid and L-rhamnose. This synthesis relies on only two protected monosaccharides and proceeds through a common disaccharide intermediate. Synthesis of this tetrasaccharide has been designed to allow for the addition of branching elements at the 4-positions of the rhamnosyl units, or further chain elongation at the 2-position.*; *Please refer to dissertation for diagrams.
Keywords/Search Tags:Synthesis
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