| This dissertation documents the racemic total synthesis of the natural products oleocanthal, geissoschizol, corynantheidol, dihydrocorynantheol, protoemetinol, and 3-epi-protoemetinol from a single synthetic intermediate. Also described are efforts to produce an optically pure supply of the common synthetic intermediate of the above described natural products.;The work described herein represents the first steps toward the development of a general strategy capable of synthesizing several structurally diverse members of the family of compounds derived from secologanin. |
