Professor Yu Rui's Law Of Prescription For Treating Insomnia

Purpose:By collecting Professor Yu Rui’s prescriptions for treating insomnia,and summarizing the rules of Professor Yu Rui’s prescriptions for treating insomnia,it provides clinical evidence and scientific research directions for the treatment of insomnia by Chinese medicine.Material and method:331 prescriptions of Professor Yu Rui for insomnia from November 2017 to November 2019 were collected,and set up a database of the prescriptions and tastes in the prescriptions.The frequency of the statistics was analyzed by frequency analysis,correlation analysis,cluster analysis,factor analysis and association rule analysis through IBM SPSS 22.0 and IBM SPSS modeler 18.0 software to complete data mining.Results:1.Prediction frequency analysis results: The total frequency of use was 498 times,with an average of 1.50 prescriptions per visit,of which Xiaochaihu Decoction was the most frequently used,71 times,with a frequency of 21.45%.2.The correlation analysis results of prescriptions have the following formulas and combinations with high correlation: Wendan Decoction-Dingzhi Pill,Wendan Decoction-Huanglian Wendan Decoction,Shengmai Yin-Feng Sui Dan,Erchen Decoction-Wuling San,Wu Lingsan-Zhenwu Decoction,Wulingsan-Fengsui Dan,Dementor Decoction-Linggui Baizhugan Decoction.3.Analysis of frequency of traditional Chinese medicine: The total frequency of use was 4701 times,with an average of 25.54 Chinese herbs per visit,of which the highest frequency was Yejiaoteng,186 times,with a frequency of 56.19%.The cumulative frequency of 22 flavors of high-frequency Chinese medicines is 2956 times,and the cumulative frequency is62.88%.The medicinal properties of Chinese medicines are the most frequently used with warm drugs,followed by slightly cold and cold.Traditional Chinese medicine has the highest frequency of sweet drugs.Traditional Chinese medicine is classified as "spleen","lung","stomach","heart" and "liver".The commonly used first-class efficacy categories of traditional Chinese medicine include tonifying deficiency medicine,relieving superficiality medicine,tranquilizing phlegm medicine,clearing heat medicine,resolving phlegm,relieving cough and asthma medicine,regulating qi medicine,promoting blood circulation and removing stasis medicine,benefiting water and infiltrating dampness medicine.The commonly used second-class efficacy categories of traditional Chinese medicine are Tonifying Qi medicine,nourishing heart and tranquilizing spirit medicine,dispersing wind and cold medicine,promoting water and swelling medicine,dispersing wind and heat medicine,clearing heat and drying dampness medicine,warming cold phlegm medicine,stabilizing liver Yang medicine,tonifying blood medicine,activating blood and relieving pain Medicine,heat clearing and phlegm resolving medicine.4.High frequency Chinese medicine correlation analysis results: The 29 flavors of high-frequency Traditional Chinese medicine correlation analysis were performed,and 10 pairs of TCM combinations were obtained: Bupleurum Scutellaria,ginger jujube,oyster keel,Zhishi Zhuru,Yuanzhi calamus,Banxia Chenpi,Zhuru Huanglian,Fuling Baizhu,Banxia Zhuru,Xiangfu Yujin.5.Factor analysis results of high-frequency Chinese medicine: Factor analysis was performed on 29 flavors of high-frequency Chinese medicine,and 9 groups of common factors were obtained,which are reflected in the characteristics of Professor Yu Rui’s treatment of insomnia in many aspects6.Analysis results of association rules of high-frequency Chinese medicine: Factor analysis was performed on 29 flavors of high-frequency Chinese medicine,and two core prescriptions were obtained,which is in line with Professor Yu Rui’s "reconciliation of the surface,Qianyang Anshen" insomnia treatment idea.Conclusion:1.According to the statistics of the frequency of the use of prescription and traditional Chinese medicine,it can be concluded that Professor Yu Rui’s main principles of insomnia treatment are "strengthening the body and removing pathogenic factors,regulating the cardinal,eliminating phlegm and calming the nerves".2.According to the statistics of the traditional Chinese medicine’s meridian tropism and efficacy categories,it can be concluded that the medicine used by Professor Yu Rui in the treatment of insomnia is mainly warm,flat,slightly cold and cold,the medicine taste is mainly sweet,bitter and bitter,the meridian tropism is mainly spleen,lung,stomach,heart and liver,and the efficacy categories are mainly tonic drugs,surface resolving drugs and tranquilizing drugs.3.According to the statistics of correlation analysis,factor analysis and association rule analysis of prescription and traditional Chinese medicine,Professor Yu Rui can get the combination of prescription and medicine in the treatment of insomnia.