| Objective:To evaluate the clinical effect of Panlong moxibustion in the treatment of chronic fatigue syndrome,and to explore the influence of Panlong moxibustion on CRH,ACTH and CORT in the serum of patients with chronic fatigue syndrome,and to reveal the mechanism of Panlong moxibustion in the treatment of chronic fatigue syndrome,so as to provide reliable basis for clinical application of Panlong moxibustion in the treatment of chronic fatigue syndromeMethods:80 patients with chronic fatigue syndrome were randomly divided into treatment group and control group,40 cases in each group.The treatment group was treated with Panlong moxibustion and the control group with electro acupuncture.The treatment group was treated once a week for three weeks.The control group was treated once a day,five times a week,for three weeks.By using fatigue Scale-14 and fatigue assessment instrument,the scores of each scale and the changes of CRH,ACTH and CORT in serum were observed before and after treatment in the two groups,and the clinical efficacy of the two groups was evaluatedResults:1.There was no significant difference in sex,age and course of disease between the two groups before treatment(P>0.05)2.There was no significant difference between the two groups in the scores of fatigue Scale-14 and fatigue assessment instrument before treatment(P>0.05)3.There was no significant difference in serum CRH,ACTH and CORT between the two groups before treatment(P>0.05)4.After treatment,fatigue scale-14 and fatigue rating scale were compared between the two groups,and the difference was statistically significant(P<0.05).The difference of scores of fatigue scale-14 and fatigue rating scale between the treatment group and the control group before and after treatment was significant(P<0.01),and the difference of scores of the treatment group was greater than that of the control group.There were significant differences in the scores of fatigue scale-14 and fatigue rating scale between the two groups before and after treatment(P<0.01)5.After treatment,serum CRH and CORT of the treatment group were significantly different from those of the control group(P<0.05),while serum ACTH of the treatment group was not significantly different from that of the control group(P>0.05).The difference of serum CRH,ACTH and CORT between the treatment group and the control group before and after treatment was significant(P<0.01),and the difference of the treatment group was greater than that of the control group.Comparison of CRH,ACTH and CORT between the two groups before and after treatment showed statistically significant differences(P<0.05)6.The total effective rate was 95.0%in the treatment group and 87.5%in the control group.The difference between the two groups was statistically significant(P<0.05)Conclusion:1.Panlong moxibustion can effectively improve the fatigue symptoms of chronic fatigue syndrome patients;2.Panlong moxibustion can increase the serum CRH,ACTH,and CORT of chronic fatigue syndrome patients,and correct and regulate the function of Hypothalamus pituitary adrenal axis. |
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