Preliminary Study On The Rules Of Prescriptions For The Treatment Of Epilepsy In Children Based On The Auxiliary Platform Of Traditional Chinese Medicine Inheritance

Objective: Through collecting relevant literature on the treatment of pediatric epilepsy by Chinese medicine in recent years,and applying TCMISS(V2.5),the prescriptions of traditional Chinese medicine(TCM)for the treatment of pediatric epilepsy we re discussed to provide a reliable basis for clinical treatment of pediatric epilepsy.Methods: Retrieved the TCM clinical research literatures collected since the establishment of the database until December 31,2018,from the three major databases of CNKI,WANGFANG and VIP,and set search terms for literature search,then obtained qualified documents according to the inclusion criteria and exclusion criteria,extracted the prescriptions of traditional Chinese medicine,entered all prescriptions into TCMISS(V2.5),at last,summarized the relevant medication rules.Results: Through searching,there were 106 articles conforming to the standard,contained 115 kinds of Chinese medicine prescriptions,191 kinds of drugs,the cumulative frequency of drugs was 1271 times.Statistics showed that there are 27 kinds of drugs that are used 15 times or more.The top ten drugs used frequently were grassleaf sweetflag rhizome,tall gastrodia tuber,uncara stem with hooks,pinellia tuber,Indian bread,scorpion,bile arisaema,stiff silkworm,liquorice root,debark peony root.The frequency of using drug properties were warm 399 times,plane 361 times,cold 327 times,cool 115 times,hot 19 times.The frequency of using drug tastes were sweet 563 times,pungent 536 times,bitter 471 times,salty 118 times,sour75 times,astringent 45 times.The frequency of using meridian tropism were liver meridian 690 times,heart meridian 477 times,spleen meridian 444 times,lung meridian 371 times,stomach meridian 235 times,gallbladder meridian 178 times,large intestinemeridian 91 times,pericardium meridian 71 times,bladder meridian57 times,small intestine meridian 30 times,and triple energizer meridian 5 times.There were 28 kinds of core drug combination,and14 kind of new prescriptions of traditional Chinese medicine from analyzing data.Conclusion: The high-frequency types of Chinese medicines used to treat pediatric epilepsy were mainly liver-pacifying wind-extinguishing medicine,tonifying medicine,phlegm-resolving medicine,tranquilizing medicine,blood-activating and stasis-resolving medicine,resuscitative medicine.In terms of four natures and five flavors,the mainly drug properties were warm,plane,and cold,the drug tastes were sweet,pungent,and bitter.In terms of meridian tropism,there were liver meridian,heart meridian,and spleen meridian.According to the excavated drug pairs and new prescriptions for the treatment of pediatric epilepsy,it can be concluded that the main causes of epilepsy in children include wind,phlegm,blood stasis,and deficiency.Therefore,the treatment methods are mainly wind-extinguishing,phlegm-resolving,blood-activating and stasis-resolving,and tonifying.