| Purpose: Based on the theory of traditional Chinese medicine,this study uses Professor Zhu Wenfeng’s dialectical theory of evidence to focus on extracting the syndrome unit of patients with gastric cancer precancerous lesions(PLGC),and analyzing the different pathological types of patients with precancerous lesions of the gastric cancer-intestinal metaplasia(IM),dysplasia(DYS)population distribution characteristics,as well as the distribution of disease and disease syndrome,provide theoretical guidance for the clinical use of traditional Chinese medicine for the treatment of the disease.Methods: In this study,118 patients who were hospitalized in the spleen and stomach ward of Liaoning Provincial Hospital of Traditional Chinese Medicine from March 2017 to July2018 were collected by the on-site questionnaire analysis.The patients were collected from different precancerous lesions of different pathological types.,finishing,including general information,endoscopy results,pathological results,four diagnostic materials of Chinese medicine,etc.,complete the TCM syndrome integral quality scale(see attached table).Then refer to the dialectical syndrome scale in the Syndrome Differentiation,written by Professor Zhu Wenfeng,and add the relevant syndromes separately.If the score is greater than or equal to 70,the patient’s syndrome and disease syndrome can be identified.Prime,and the information obtained into the Excel table,using SPSS 20.0 software for data analysis,exploratory study of gastric cancer precancerous lesions of different pathological types,different pathological grades of the distribution of syndromes.Results: 1.Of the 118 PLGC samples,98(83.05%)were in the intestinal metaplasia group and 20(16.95%)in the dysplasia group.Among them,there were 54 cases of mild intestinal metaplasia,32 cases of moderate intestinal metaplasia,12 cases of severe intestinal metaplasia,11 cases of mild dysplasia,6 cases of moderate dysplasia,and 3 cases of severe dysplasia.2.Gastroscopic findings were diagnosed as atrophic gastritis in 82 cases(69.49%),non-atrophic gastritis in 33 cases(27.97%),and gastric ulcer in 3 cases(2.54%).Among them,there were 72 cases of atrophic gastritis in the intestinal metaplasia group,26 cases of non-atrophic gastritis,0 cases of gastric ulcer,10 cases of atrophic gastritis in the dysplasiagroup,and 7 cases of non-atrophic gastritis.There are 3 cases of ulcers.Statistical analysis of the distribution of gastroscopic results of different pathological types showed significant statistical differences.3.Of the 118 PLGC samples,56 were male(47.46%),62 were female(52.54%),and the ratio of male to female was 0.9:1.4.Among the 118 PLGC samples,the youngest was 34 years old,the oldest was 80 years old,and the average age was 62.03±9.335 years old.The overall age distribution was mainly middle-aged and elderly.5.In 118 cases of PLGC,the syndromes were mainly gastric,spleen and liver,and also included multiple organs such as chest,gall,kidney and large intestine.Among them,in 98 cases of intestinal metaplasia,the mild intestinal metaplasia focused on the stomach and liver;the moderate intestinal metaplasia focused on the stomach and spleen;the severe intestinal metaplasia focused on the stomach and spleen.And kidney;in 20 cases of dysplasia samples,there was no statistical difference in the distribution of syndromes.6.Among the 118 PLGC samples,the disease syndrome mainly consisted of qi stagnation,qi deficiency and heat,and also included wet,phlegm,blood stasis,yang deficiency,yin deficiency and Jin deficiency.Among them,in 98 cases of intestinal metaplasia,the disease syndrome of mild intestinal metaplasia was mainly qi stagnation;the disease syndrome of moderate intestinal metaplasia was mainly heat;the disease syndrome of severe intestinal metaplasia was mainly Bloody,qi deficiency and yang deficiency.In 20 cases of dysplasia group,the disease syndrome of mild dysplasia was mainly qi stagnation;the disease syndrome of moderate dysplasia was mainly heat and qi deficiency;the disease syndrome of severe dysplasia was mainly blood stasis,Qi deficiency and yang deficiency.Conclusion:1.The clinically affected population of PLGC is mainly middle-aged and elderly people.The pathological type is more common in intestinal metaplasia.The endoscopy results are mainly atrophic gastritis.2.PLGC disease syndrome mainly consists of stomach,spleen and liver,and also includes multiple organs such as chest,gall,kidney and large intestine;the main syndromes are mainly qi stagnation,heat and qi deficiency,including wet,sputum,blood stasis,yang deficiency,yin deficiency,Jin deficiency,etc.The pathogenic characteristics of this disease aremulti-disease and multi-pathogenic.3.The mild intestinal metaplasia focuses on the stomach and liver,the main disease is qi stagnation;the moderate intestinal metaplasia focuses on the stomach and spleen,the disease is mainly heat;the severity of intestinal metaplasia Focus on the stomach,spleen and kidney,the main disease is blood stasis,qi deficiency and yang deficiency4.The mild dysplasia is mainly caused by qi stagnation;the moderate dysplasia is mainly caused by heat and qi deficiency;the severity of severe dysplasia is mainly blood stasis,qi deficiency and yang deficiency. |
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