Observation On The Effect Of Zhigancao Decoction Assisting The First-stage Cardiac Rehabilitation In The Treatment Of Patients With Deficiency Of Both Qi And Yin After CABG

Purpose: The short-term efficacy of the application of Zhigancao Decoction in the treatment of patients with Qi-Yin deficiency after coronary artery bypass grafting(off-pump CABG)was performed.Material and method:From October 2017 to October 2018,the cardiovascular surgery of the General Hospital of the Northern Theater was diagnosed as coronary heart disease and the off-pump CABG was successfully performed.The postoperative TCM syndrome differentiation was 80 patients with Qi-Yin deficiency syndrome type,using a random number table.The method was divided into the rehabilitation group(test group)treated with integrated Chinese and Western medicine and the rehabilitation group(control group)of conventional treatment.40 cases in each group were given conventional western medicine treatment and including sports training,psychological counseling,health education,etc.In the routine stage I cardiac rehabilitation,the experimental group added Chinese herbal medicine Zhigancao decoction on the basis of this,7 days as a course of treatment,and 2 courses of treatment,respectively,to observe the symptom score of TCM symptom after treatment,NYHA cardiac function classification,NT-pro BNP,Tn T,Seattle Angina Scale(SAQ)score and safety indicators.Results:1.TCM symptom score: Both groups improved significantly before and after treatment(p<0.05),and the TCM symptom score of the treatment group improved significantly compared with the control group(p<0.05);2.Heart function classification: the heart function of the treatment group before and after treatment There was a significant difference in graded(NYHA)(p<0.05).3.Tn T: There was no significant difference between the two groups before treatment(p>0.05).There was a statistically significant difference between the two groups after treatment(p> <0.05);4.NT-pro BNP: Both groups were significantly lower than before treatment.Compared with the components before and after treatment,the improvement of NT-pro BNP in the experimental group was better than that in the control group(p<0.05);5.SAQ score: treatment The latter two groups were lower than the intra-group ratio(p<0.05);PL,AS and DP scores were statistically different between the two groups after treatment(p<0.05);AF and TS scores,the same period after treatment There were no significant differences(p>0.05).There was no significant difference in AS,AF and TS scores between the groups before and after treatment(p>0.05).The difference of PL and DP scores was statistically significant(p<0.05).6.Safety aspects,blood coagulation,liver and kidney function,biochemistry and blood routine after treatment Safety showed no abnormalities.Conclusion: Application of Zhigancao Decoction in the treatment of stage I cardiac rehabilitation can significantly reduce NT-pro BNP and Tn T in patients with off-pump CABG,improve exercise capacity,reduce clinical symptoms,improve quality of life,and have remarkable curative effect.It is excellent in improving TCM symptoms and SAQ scores.It is a normal heart rehabilitation and is safe.