Laparoscopy And Open Surgery In The Treatment Of Early Cervical Squamous Cell Carcinoma Of The Clinical Efficacy Analysis And The Effect Of Kangai Injection On The Prognosis Of Cervical Cancer

Purpose: To compare the clinical efficacy of open surgery and laparoscopic surgery for early cervical squamous cell carcinoma,and to discuss the effect of Kangai injection on the prognosis of early cervical cancer.Material and method:Retrospective analysis of IB1-IIA1-compliant early cervical squamous cell carcinoma in the Department of Gynecology,Liaoning Provincial Cancer Hospital from January 1,2012 to December 31,2016,and undergoing radical hysterectomy and pelvic lymphadenectomy were enrolled.The patients were divided into a laparoscopic radical hysterectomy group and a transabdominal hysterectomy group.The clinical data of the two groups were collected including age,clinical stage,degree of differentiation,etc.The duration of surgery,hemoglobin change,intraoperative blood loss,blood transfusion,number of positive lymph nodes,number of lymph nodes,intraoperative and postoperative complications were compared between the two groups.Middle ureteral injury,intraoperative bladder injury,postoperative thrombosis,postoperative intestinal obstruction,postoperative lymphedema,postoperative abdominal pelvic activity,postoperative urinary retention,DFS,OS On the basis of the previous medical records,the group was divided into the experimental group using Kangai injection,and no adjuvant treatment was used as the control group.The hospitalization time of the two groups,WBC,before and after treatment,and ALT,AST,SCC,hospital stay,DFS,OS.Comparison was made by statistical analysis.Results:1.The operation time of laparoscopic group and open group was significantly longer than that of open group(p<0.05).2.The amount of bleeding,blood transfusion and hemoglobin change were slightly lower in the laparoscopic group than in the open group(p<0.05).The rate of nonunion incision in open surgery was greater than that in the laparoscopic group.There was a statistically significant difference between the two groups(P<0.05).The side injury of laparoscopic surgery was significantly higher than that of open group(P<0.05).3.There was no significant difference in DFS and OS between laparoscopic group and open group in one year,three years and five years(P>0.05).4.There were no significant differences in WBC,ALT,AST and SCC between the two groups before and after treatment(P>0.05).5.There were no significant differences in DFS and OS between the observation group and the control group in one year,three years and five years(P>0.05).Conclusion:1 Laparoscopic surgery,with less intraoperative bleeding,less infection of the incision,faster postoperative healing,no significant difference in postoperative recurrence rate and mortality compared with open surgery,is a safe and feasible means of treating cervical cancer;2 Compared with open surgery,laparoscopic surgery takes a long time,and the risk of secondary injury during surgery is high;3 The application of Kangai injection had no significant effect on PFS and OS after radical resection of early cervical cancer;...