| Purpose: Based on 316 cases of type 2 diabetes,the distribution of TCM syndrome type and glucolipid metabolism correlation among different syndrome types,according to different glucolipid metabolic control level for clinical T2 DM patients with evidence-based medicine to provide the reference.Material and method:In March 2017 to July 2017 in liaoning university of traditional Chinese medicine hospital endocrinology in hospital patients,with reference to the 2013 edition of "Chinese type 2 diabetes prevention guide about T2 DM diagnosis standard screening 316 T2 DM patients,using SPSS2.0 software for general data,laboratory examination results,complications and descriptive analysis of syndromes of traditional Chinese medicine,analysis the distributing rule and different syndrome types glucolipid metabolism index difference between TCM syndrome type.Respectively according to blood glucose and blood lipid control target is divided into four groups(blood glucose is in the standard range group,the blood sugar exceeds the standard value range group,the blood fat is in the standard value range group,the blood fat exceeds the standard value range group),the analysis of the distribution characteristics of TCM syndrome types in each group,and between different TCM syndrome types of the difference between glucolipid metabolic indices.Results: 1.The total number of cases was 316,with 182 males and 134 females,aged between 24 and 80 years,and the duration of the disease was between January and 30 years,and the patients were mostly in the 50-70 age group.Patients with a history of smoking(65 cases,20.57%)had a history of alcohol consumption(40 cases,12.66%).In family history,patients with family history of diabetes(134 cases,42.11%)had family history of hypertension(20 cases,6.33%).In terms of age,compared with the deficiency of both qi and yin,deficiency of both qi and yin with blood stasis,damp-hrat trapped spleen with blood stasis anddeficiency of both yin and yang with blood stasis were statistically significant(P < 0.01).In terms of course of disease,compared withdeficiency of both yin and yang with blood stasis,there was a statistical difference between damp-hrat trapped spleen with blood stasis(P < 0.05).Compared with thedeficiency of both yin and yang with blood stasis,there was a significant statistical difference betweendamp-hrat trapped spleen(P < 0.01).In terms of WC value,compared with thedeficiency of both qi and yin with blood stasis there was a statistically significant difference between thedamp-hrat trapped spleen with blood stasis anddeficiency of both yin and yang with blood stasis(P < 0.05).2.The study found that in 316 cases of T2 DM patients,TCM syndrome total rule from high to low respectively,deficiency of both qi and yin with blood stasis type 241 cases(76.27%),damp-hrat trapped spleen with blood stasis type 56 cases(17.72%),damp-hrat trapped spleen type 8 cases(2.53%),qi and Yin deficiency type 6 cases(1.90%),deficiency of both yin and yang with blood stasis 5 cases(1.58%).In blood glucose is in the standard range group,TCM syndrome type distribution of deficiency of both qi and yin with blood stasis type 48(81.36%),damp-hrat trapped spleen with blood stasis type of 10(16.95%)and deficiency of both yin and yang with blood stasis type 1(1.69%),nodamp-hrat trapped spleen type and deficiency of both qi and yin.In the blood sugar exceeds the standard value range group,the TCM syndromes were divided into deficiency of both qi and yin with blood stasis type 193(75.10%),damp-hrat trapped spleen with blood stasis type 46(17.90%),damp-hrat trapped spleen type 8(3.11%),deficiency of both qi and yin type 6(2.33%),deficiency of both yin and yang with blood stasis type 4(1.56%).In the blood fat is in the standard value range group,the syndromes of TCM syndromes were 20(6.33%)ofdeficiency of both qi and yin with blood stasis type,and 1(0.31%)of damp-hrat trapped spleen with blood stasis type,without deficiency of both yin and yang with blood stasis,damp-hrat trapped spleen,and deficiency of both qi and yin.In the blood fat exceeds the standard value range group,the syndromes of TCM syndromes were 220(69.62%)of deficiency of both qi and yin with blood stasis,55(17.41%)of damp-hrat trapped spleen with blood stasis,damp-hrat trapped spleen type 8(2.53%),deficiency of both qi and yin type 7(2.22%)and deficiency of both yin and yang with blood stasis type 5(1.58%).3.In terms of diabetic chronic complications,qi and Yin deficiency type of diabetes-related complications in patients with the least,only merge MS patients in 2 cases(33.33%),qi and Yin deficiency and blood stasis type related complications in patients with the most species and amount.The prevalence rate of AS in all patients with TCM syndrome was the highest,with the lowest prevalence of diabetic foot.4.This study found that compared with the blood glucose is in the standard range group,the TC,TG,LDL-C,HOMA-IR of the blood sugar exceeds the standard value range group were all increased,and hdl-c of the blood sugar exceeds the standard value range group decreased.Compared with the blood fat is in the standard value range group,HbA1 c,FPG and HOMA-IR of the blood fat exceeds the standard value range group all increased.Compared with the blood glucose is in the standard range group,there was statistically significant difference between TC and LDL-C in the blood sugar exceeds the standard value range group.(P < 0.05);there was significant statistical difference between HOMA-IR in the blood fat exceeds the standard value range group(P < 0.01).5.HbA1 c,FPG,and HOMA-IR were the highest in damp-hrat trapped spleen,while TC and ldl-c were the highest in deficiency of both yin and yang with blood stasis,and HDL-C was the lowest in damp-hrat trapped spleen with blood stasis.In terms of TC,compared with deficiency of both yin and yang with blood stasis,the deficiency of both qi and yin with blood stasis and damp-hrat trapped spleen of TC were statistically significant(P < 0.05).in the blood sugar exceeds the standard value range group and the blood fat exceeds the standard value range group,Compared with deficiency of both yin and yang with blood stasis,TC was still statistically significant(P < 0.05)in deficiency of both qi and yin with blood stasis and damp-hrat trapped spleen with blood stasis.LDL-C was statistically significant(P < 0.05)in damp-hrat trapped spleen with blood stasis and deficiency of both qi and yin with blood stasis.In the blood sugar exceeds the standard value range group,HDL-C was statistically significant(P < 0.05)in deficiency of both qi and yin with blood stasis anddamp-hrat trapped spleen with blood stasis.In the blood fat exceeds the standard value range group,HDL-C was statistically significant(P < 0.05)in deficiency of both qi and yin with blood stasis anddamp-hrat trapped spleen with blood stasis.Conclusion: 1.The deficiency of both qi and yin with blood stasis are the most common TCM syndromes in T2 DM,and the second is the damp-hrat trapped spleen with blood stasis,damp-hrat trapped spleen,deficiency of both qi and yin,and deficiency of both yin and yang with blood stasis.In the condition of different blood glucose and lipid,the distribution of TCM syndromes is consistent.The distribution of syndromes is related to the course of disease,age and obesity.2.The type of chronic complications of diabetes was the lowest in the deficiency of both qi and yin,and the type of chronic complications of diabetes with the deficiency of both qi and yin with blood stasis was the most.In the related chronic complications of diabetes,AS has the highest prevalence in various TCM syndromes,and the abnormal lipid metabolism affects T2 DM patients continuously,and the coexistence lies in all stages of diabetes.3.IR,as an important factor leading to the disorder of sugar and lipid metabolism,persisted in the course of T2 DM,and existed in various TCM syndromes,especially in the case of damp-hrat trapped spleen.4.The TC,LDL-C,HOMA-IR and HbA1 c are positively correlated,and the strict control of blood glucose in the target range can reduce the occurrence and development of diabetes lipid metabolism disorder,and effectively reduce IR.HbA1 c was tested regularly to evaluate the effect of blood glucose and lipid in T2 DM patients.5.TC,LDL-C and T2 DM are related to TCM syndromes,and LDL-C has a correlation with T2 DM TCM syndromes when blood glucose and/or blood lipid control are not good. |
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