| Objective:1.Diuresis of Cinnamomum cassia and Cinnamomum Cassia is more abundant and powerful in literature,which provides a more solid and complete theoretical basis for its effective application in clinical practice.2.To clarify the diuresis mechanism of Cinnamomum cassia and Cinnamomum cassia.3.To summarize the indications,compatibility and dosage characteristics of Cinnamomum cassia and Cinnamomum Cassia in compound prescription.4.To construct the relationship between the syndromes of diuretic action of Cinnamomum cassia and the dosage of drugs.5.To compare the diuretic effects of Cinnamomum cassia and Cinnamomum cassia.Methods:1.Summarize and summarize the literature of the past dynasties on the diuretic effects of Cinnamomum cassia and Cinnamomum Cassia by using the method of combing Chinese medical literature.2.The descriptive statistical analysis and association rule analysis of the literature were carried out by using the ancient and modern medical case cloud platform software(V1.4).Results:l.During the Han and Tang Dynasties,the medicinal parts of Cinnamomum cassia and Cinnamomum Cassia were branches and bark;during the Song,Jin and Yuan Dynasties,the medicinal parts of Cinnamomum cassia and Cinnamomum Cassia were differentiated and their names and facts evolved.The medicinal parts of Cinnamomum Cassia were tender bark and tender branches,and the medicinal parts of Cinmamowum Cassia were branches and dry bark;in the Ming and Qing Dynasties,the medicinal differentiation and name and substance of Cinnamomum Cassia were widely accepted During this period,the differentiation of Cinnamomum cassia and Cinnamomum Cassia was finally clear and unified.2.From the Warring States Period to the Eastern Han Dynasty,the basic understanding of the efficacy of Cinnamon Branch was established;from the Jin Dynasty to the Sui and Tang Dynasties,doctors mainly inherited the efficacy of Cinnamon Branch and Cinnamon Branch;during the Song,Jin and Yuan Dynasties,the efficacy of Cinnamon Branch and Cinnamon Branch was distinguished,and Cinnamon Branch focused on the treatment of superficial diseases and diseases on the top;Cinnamon focused on the treatment of viscera diseases In the Ming and Qing Dynasties,the understanding of the effect of Cinnamomum Cassia on liver,lung and Qi was deepened,and the effect of Cinnamomum Cassia on warming and invigorating the life,igniting fire and returning to the original state was expounded in depth.3.In the research of herbal literature,112 ancient and modern herbal works were identified,and finally included in the literature records of 20 cinnamon branches and diuretic effects of cinnamon.The herbal monographs on the diuretic effects of Cinnamomum cassia and Cinnamomum Cassia appeared late and were recorded in the Ming Dynasty.Pharmacologists have elucidated the diuretic effects of Cinnamomum cassia and Cinnamomum cassia,but they all think that the diuretic effects of the two drugs are closely related to their pungency and warmth.From the perspective of viscera,the diuretic effects of Cinnamomum cassia and Cinnamomum Cassia are related to the urinary bladder,lung,spleen,kidney and other viscera,mainly because they can warm and invigorate Yang Qi,and guide other drugs into the bladder.It is caused by the action of meridians.4.In the research of medical prescription literature,more than 90,000 prescriptions contained in the Dictionary of Traditional Chinese Medicine Prescriptions were searched manually,and 135 prescriptions were finally included.The diuretic effect of Cinnamomum cassia and Cinnamomum Cassia in prescriptions is mainly found in the treatment of three diseases:diarrhea,edema and gonorrhea;the syndrome diagnosis is mainly based on four syndrome types:Yang deficiency and water flooding,dampness-heat intrinsic syndrome,spleen deficiency and dampness trapped syndrome;the frequency of the main symptoms is the highest in the record of the two stool symptoms,waist-abdomen symptoms and thoracic-hypochondriac symptoms.In the prescription,Cinnamomum cinnamomi and Cinnamomum cinnamomi are mainly compatible with water and dampness-promoting drugs,Qi-regulating drugs,Wenli drugs,tonics and other drugs.Among them,cinnamon is mainly compatible with Poria cocos,Atractylodes macrocephala,Alisma orientalis,Polyporus umbellatus and Plantago seed.The dosage compatibility ratio of Cinnamon and Porna cocos was 1:1 and 1:3 with the highest frequency.In the decoction,the average dosage of Cinnamomum cassia twig was close to that of Cinnamomum cassia,about 6.0g,but the dosage distribution range of Cinnamomum Cassia was wider.The dosage of compatibility of Alisma orientalis and Polyporus umbellatus is relatively small,while the dosage of Rhizoma Atractylodis for invigorating qi and invigorating spleen and Radix Rehmanniae for tonifying blood and nourishing Yin are relatively large.5.In the literature study of medical records,more than 18,000 medical records were retrieved manually,and 150 medical records were finally included.Cinnamomum cassia and Cinnamomum Cassia play a diuretic role in medical records,in which the diagnosis of TCM name is mainly found in four diseases,such as edema,diarrhea,gonorrhea and swelling.The diagnosis of Western medicine name is mainly found in urinary system diseases,circulatory system diseases and digestive system diseases.In medical records containing Cinnamomum cassia,its syndrome diagnosis is mainly Yang deficiency and water flooding syndrome,spleen deficiency and dampness syndrome,wind-water flooding syndrome and dampness syndrome.There are six syndromes,such as heat syndrome,Qi stagnation and water stopping syndrome,Water-dampness flooding syndrome,etc.Among the medical cases containing cinnamon,the diagnosis of syndromes is mainly based on Yang deficiency and water flooding syndrome,damp-heat syndrome and other two syndromes.In medical records,the main symptoms were duodenal symptoms,lumbar and abdominal symptoms and chest and hypochondriac symptoms.In the prescription,Cinnamomum cassia and Cinnamomum Cassia are mainly compatible with the drugs of diuresis and dampness,Wenli medicine,Qi-regulating medicine,heat-clearing medicine,tonic medicine,etc.Among them,Cinnamomum Cassia is mainly compatible with Poria cocos,Alisma orientalis,Polyporus umbellatus,raw Atractylodes macrocephala;Cinnamomum Cassia is mainly compatible with Poria cocos,Alismatis orientalis,Radix Plantagonii,Aconiti can The dosage compatibility ratio of Cinnamomum cassia and Poria cocos was 1:2 and 1:3,and that of Cinnamomum cassia and Poria cocos was 1:4.In the prescription,the dosage of Cinnamomum cinnamomi is larger than that of Cinnamomum cinnamomi.The dosage of common hygroscopic and dampness-reducing drugs used in the compatibility is within the range of the usual dosage,but the dosage of Poria cocos is relatively large.Conclusion:1.The understanding of the medicinal parts and efficacy of Cinnamomum cassia and Cinnamomum Cassia has a historical evolution.Under the constant construction of the theoretical system of traditional Chinese medicine,it gradually evolved under the influence of social,political,economic,cultural and climate change factors of past dynasties,and finally reached a consensus.2.The diuretic effect of Cinnamomum cassia and Cinnamomum Cassia is mainly manifested in the three diseases of diarrhea,edema and gonorrhea.The main indications are Yang deficiency and water flooding,spleen deficiency and dampness trapping,dampness-heat intrinsic syndrome and Water-dampness flooding syndrome.In prescriptions,they are mainly compatible with water-regulating and dampness-regulating drugs,Qi-Regulating drugs,warming-inside drugs,tonics and heat-clearing drugs.Among the three prescriptions,the dosage of Cinnamomum Cassia for diuresis was close to or slightly larger than that of Cinnamomum cassia,and the dosage range of Cinnamomum Cassia was wider than that of Cinnamomum cassia.3.Cinnamon diuretic effect is more widely used than Cinnamon twig,Cinnamon twig is suitable for the use of urinary disadvantage and symptoms;Cinnamon is suitable for the use of yang-qi deficiency,especially in the case of kidney fire insufficiency and urinary disadvantage. |