| Information:Knee osteoarthritis is a degenerative disease that is becoming more a nd more young due to lifestyle changes and changes in diet.Massage is a distinctive external treatment method in Chinese medicine.Its non-invasive and non-side-effects m ake the population highly accepted.There is a large amount of literature indicating th at massage therapy has a good effect on the improvement of pain symptoms of knee osteoarthritis.Pain is the fifth vital sign of human beings.Its signal is transmitted to the cerebral cortex via the nerve.Chinese medicine believes that massage has the dual roles of shape modulation and tone adjustment.However,the mechanism of massage and analgesia is mostly concentrated in animal experiments.Focusing on local effects,the development of contrast-enhanced ultrasound and functional magnetic resonance in recent years provides a basis for studying the local and central mechanisms of massa ge for knee osteoarthritis.Objective:To observe the effects of massage therapy on brain function network a nd local microcirculation in patients with knee osteoarthritis,thus illustrating the dual role of massage in the adjustment and adjustment of knee osteoarthritis patients.Method:For 19 female patients with pain-related symptoms that met the diagnosti c criteria for knee osteoarthritis,the unilateral knee with the heaviest pain was selecte d for 6 weeks of massage treatment.The massage program was based on the famous doctor of the capital,Professor Sun Chengxiang.The nine-step and eight-point method was established for treatment.All acupoint positioning was carried out with reference to the name and location of the acupoint(the national standard GB/T12346-006 of th e People's Republic of China),Baseline assessments were performed on all subjects pr ior to treatment initiation,demographic data were collected,and pain digital scoring w as used before the first treatment,after the first treatment,and after the sixth treatmen t(Numerical Rating)Scale,NRS)and The Western Ontario and McMaster Universities Arthritis Index(WOMAC)to assess the extent of pain improvement,as well as trans cranial ultrasound findings and structural magnetic resonance and functional magnetic r esonance imaging Scanning,analysis of NRS and WOMAC index,rectus femoris micr ocirculation and functional magnetic resonance before and after treatment of patients th emselves.Results:Twenty subjects enrolled in the study completed baseline assessment,and one patient fell off during treatment;the remaining 19 patients completed 6 treatment s twice a week.The age of 19 subjects ranged from 41 to 69 years,with a course o f disease between 1 and 10 years.Each subject received the highest severity of unilat eral.knee treatment,including 10 cases of left knee.9 cases of right knee.NRS scale scores before and after treatment,WOMAC index and peak time of contrast-enhanced ultrasound perfusion imaging,contrast agent concentration were compared by SPSS20.0 for one-way repeated measures analysis of variance.1.The NRS scores of the subj ects before the first treatment,after the first treatment and after the sixth treatment w ere 5.26 ± 1.17,3.08 ± 1.27 and 1.79 ± 1.00,respectively.After the first treatment,t he NRS score was significantly lower than that before the first treatment(P<0.001),a nd the NRS score after the sixth treatment was significantly lower than that before th e first treatment(P<0.001),and the NRS score after the sixth treatment.After the firs t treatment,it decreased(P<0.05).The WOMAC index scores of the subjects before t he first treatment,after the first treatment and after the sixth treatment were 23.37±8.26,21.79±11.93 and 17.89±13.41,respectively.After the first treatment,the WOMAC i ndex score was lower than that before the first treatment,and the difference was not statistically significant(P>0.05).The WOMAC index score after the sixth treatment w as significantly lower than that before the first treatment(P<0.05).The difference was statistically significant;the WOMAC index score after the sixth treatment was lower than that after the first treatment,and the difference was not statistically significant(P>0.05).There was no significant difference in TTP before and after treatment,but there was no statistical significance(P was greater than 0.05).There was a difference in P I before and after treatment.The difference was statistically significant(P<0.05):3.T he right brain after the first massage The hemisphere buckled back,the middle of the forehead,the central anterior gyrus,and the medial side of the forehead changed.Aft er six gains of massage,the fusiform and sacral gyrus of the left hemisphere of the b rain changed.Conclusion:1.Tuina treatment can significantly improve the pain symptoms of kn ee osteoarthritis patients,the degree of improvement is positively correlated with the n umber of treatments;2.Tuina can adjust the changes of pain-related brain function ne twork,and the transient effects of single treatment and multiple times There is a diffe rence in the cumulative effect after treatment;3.Tuina therapy can improve the micro circulation of the rectus femoris muscle and adjust the metabolic state,but the observ ation period of this experiment is short,and the peak time of the rectus femoris perfu sion imaging is not obvious,and it is not statistically significant.The above conclusio ns support the dual role of massage in the treatment of knee osteoarthritis patients.T his test is a pioneering clinical dual mechanism research,but the sample size is small,the technical methods used are not standardized,and it is recommended.In the next step,we can carry out research on the basic mechanism of massage,which is more ri gorous,more quantifiable,and larger in sample size. |
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