Study On The Correlation Between Depression After Acute Cerebral Infarction And The Degree Of Cerebrovascular Stenosis

Objective To explore the relationship between depression after acute cerebral infarction and the degree of cerebral vascular stenosis,and to provide help for the prevention and treatment of post-stroke depression.Methods A total of 120 patients with acute cerebral infarction for the first time were admitted to the department of neurology of the People's Hospital of Guangxi Zhuang Autonomous Region between January 2017 and January 2018.Acute cerebral infarction was diagnosed based on brain CT or brain MRI.Patients were assessed with 24 Hamilton Depression Scales to estimate the presence of depression.It was divided into 82 cases of non-depression after acute cerebral infarction and 38 cases of depression after acute cerebral infarction.According to the blood circulatory system,there were 82 cases in the precirculat ory system and 38 cases in the posterior circulation system.All patients with acute cerebral infarction were examined using a 128-slice spiral CT scanner for head and neck CTA to understand the degree of vascular stenosis.Respectively to compare The degree of head and neck artery stenosis between the non-depression group and the depression group,and observe to the different of the post-stroke depression between the anterior circulatory system and the posterior circulation system.The comparison between post-stroke depression and vascular stenosis was made,and the factors related to post-stroke depression was calculated.Results 1.Comparison of head and neck arterial stenosis between the group of non-depression and the group of depression: there was a statistically significant difference in the rate of stenosis between the group of non-depression and the group of depression(P<0.01).2.Comparison of the degree of vascular stenosis in post-stroke depression: The incidence of PSD in mild group was significantly lower than that in moderate group,moderate-severe group,and occlusion group,and the differences were statistically significant(P<0.05).3.There were differences in the occurrence of PSD between the anterior and posterior circulation blood supply system(P<0.01).The incidence of PSD in patients with anterior circulatory system vasculature was significantly higher than that in patients with posterior circulatory system vasculature.4.The logistic regression analysis of the impact of different factors on the incidence of PSD: gender,age had no significant impact on the occurrence of PSD(P> 0.05).The degree of vascular stenosis,blood supply system,smoking,and NIHSS score on admission had a significant impact on PSD(P<0.05).Conclusions 1.Cerebral atherosclerosis is a factor of depression after acute cerebral infarction.2.The occurrence of depression after acute cerebral infarction is related to the degree of cerebral atherosclerosis.3.Anterior circulatory system vascular lesions The depression after acute cerebral infarction is higher than that of posterior circulation system vascular lesions.4.The severity of neurological deficits is a risk factor for depression after acute cerebral infarction.Smoking may be a protective factor for depression after acute cerebral infarction.