Research On The Key Technology Of Fluorescence Peritoneal Endoscopic Imaging System

Optical molecular imaging technology is usually used to observe the focus directly in the process of minimally invasive treatment,in order to achieve the purpose of accurate treatment.Through the accurate navigation of images,the treatment of diseases can be more accurate,systematic and perfect.In this paper,ICG is used as a fluorescent agent to build a fluorescence abdominal endoscope imaging system,calibrate the camera of the imaging system,and propose a fast fusion algorithm to achieve accurate tumor labeling and display.The main contents of this paper are as follows:(1)the construction of fluorescence abdominal endoscope imaging system.The excitation light source composed of 780 nm ± 20 nm near-infrared light-emitting diode is used to irradiate the ICG to produce the fluorescence information with the wavelength of 810 nm.The white light source composed of white light-emitting diodes is used to illuminate the field of vision of endoscope and generate the imaging information under white light;the fluorescence image and visible light image are collected by CMOS camera respectively;the data is transmitted by the main control board and acquisition card;finally,the dual channel imaging of the fluorescence abdominal endoscope system is realized by processing at the PC end.(2)study on the calibration method of fluorescence abdominal endoscope imaging system.It is one of the key technologies to improve the effect of endoscope distortion and realize fast calibration.A stereo calibration structure is proposed,which aims at the situation that the radial distortion of the endoscope is large and the user does not know the calibration knowledge.The calibration can be completed by taking an image of the calibration target.The experimental results show that the calibration process of the proposed calibration method is fast and stable,and the operation is simple,and the accuracy can reach the accuracy of the calibration based on the plane calibration plate.(3)research on fusion algorithm of fluorescence abdominal endoscope imaging system.High quality and fast fusion of fluorescence image and visible light image is one of the most important key technologies of fluorescence abdominal endoscope imaging system.A fast fusion algorithm based on saliency detection and fluorescence information enhancement is proposed.The fusion image of fluorescence and visible light image is used to mark the tumor,and the saliency detection and coefficient enhancement matrix are used to enhance the tumor details.The results show that the proposed fusion algorithm can provide a good visual effect,and is superior to the comparison algorithm in peak signal-to-noise ratio,mutual information,edge retention and other indicators.(4)the software design of the imaging system of fluorescence abdominal endoscope.In order to realize the good interactivity of the imaging system,the software of the imaging system is designed and built.It can realize the functions of information management,imaging display and report management,and basically meet the requirements of medical endoscope operation software.