The Construction Of V₂O₅-ZnO@SiO₂ Composite Antibacterial Material And Its Antibacterial Mechanism

Human health and life safety are greatly threatened by bacteria,molds and other pathogenic microorganisms.Therefore,the study on safe and efficient of antibacterial materials has important practical significance.Znic-based antibacterial materials has the advantages of good stability,wide range of antibacterial activities,no resistance to drug resistance and good biocompatibility,etc.Hence,the research of Znic-based antibacterial materials is significant,and it will be widely used in the field of antibacterial.The V₂O₅-ZnO@SiO₂ composite antibacterial materials was fabricated by hydrothermal method under the atmospheric pressure,employing mesoporous SiO₂ as a carrier,ZnO as an antibacterial agent,and V₂O₅ as a dopant,the as-obtained V₂O₅-ZnO@SiO₂ composite antibacterial materials exhibited outstanding antibacterial properties toward the E.coli and S.aureus.The basic morphology,crystal structure and chemical composition of the V₂O₅-ZnO@SiO₂ composite antibacterial materials were characterized by SEM,particle size distribution,BET,XRD,TEM and XPS.It was found that after doping V₂O₅,the morphology of ZnO crystal in V₂O₅-ZnO@SiO₂ composite antibacterial materials was changed from flower shape to nano-sheet aggregate structure.The main growth direction of ZnO crystal was changed from[0001]to[1000]facets,and the main exposed facets was changed from{01^-10}to{2^-1^-10}facets.In addition,the nano-sheet aggregate structure of ZnO has a larger specific surface area and a smaller grain size.The photochemical property of V₂O₅-ZnO@SiO₂ composite antibacterial materials was analyzed by UV-vis spectrum and PL spectrum.It was found that V₂O₅-doping can effectively reduce the band gap energy of ZnO in ZnO@SiO₂ composite antibacterial materials,which was beneficial to improve the electronic transition efficiency.Meanwhile,the electron-hole recombination rate was greatly reduced on the composite materials,which will enhance the photochemical activity of V₂O₅-ZnO@SiO₂ composite antibacterial materials and promote the production of reactive oxygen species.In addition,the antibacterial mechanisms of V₂O₅-ZnO@SiO₂ composite antibacterial materials were assessed by slow-release dissolution test,reactive oxygen species test and contact antibacterial test.The results showed that V₂O₅ promotes the dissolution of Zn²⁺/ZnO nanoparticles,enhances the production of reactive oxygen species and improves the degree of mechanical damage to bacteria in V₂O₅-ZnO@SiO₂ composite antibacterial materials.Therefore,the V₂O₅-ZnO@SiO₂composite antibacterial materials has better antibacterial activity.Finally,the antibacterial mechanisms of V₂O₅-ZnO@SiO₂ composite antibacterial materials were preliminary analyzed by SEM characterized bacteria.