Statistical Analysis Of Survival Data Based On Twin Support Vector Regression

The objective of this paper is to provide a new algorithm for the regression of survival data.We propose an algorithm of Survival twin support vector regression(STWSVR),an extension of Twin support vector regression(TWSVR)in binary classification,to explore the analysis of survival data with right censoring.The main algorithm STWSVR is to solve a pair of quadratic programming problems(QPPs) with some tuning parameters.The performance of the algorithm is compared with the survival SVR(SSVR),Cox proportional hazards regression model,Cox propor-tional hazards model with lasso regularization(Cox-lasso),random survival forests and generic gradient boosting algorithm on one simulated dataset and 6 practical clinical datasets,using two evaluation measures,C-index and Logrank x~2-statistic.