| ObjectiveTo explore the clinical characteristics,laboratory examinations,syndromes,and physical type distribution of patients with plaque psoriasis with obesity,aiming to provide a basis for personalized prevention and treatment of the disease in the future.MethodsThe plaque psoriasis patients with obesity who were treated in the dermatology department of the Affiliated Hospital of Tianjin Academy of Chinese Medicine from June2018 to December 2019 were collected.Conduct general surveys on gender,age,etc.,disease-related data and constitution types,record them in an Excel table,apply SPSS20.0software to analyze and process the data,and draw conclusions.Results1 In this study,there were 127 males(64.80%)and 69 females(35.20%),with a male to female ratio of 1.84:1.The youngest person was 23 years old,the oldest person was 68 years old,and the average age of visit was(45.44±11.48)years old.81 cases(41.33%)were 18-44years old,96 cases(48.98%)were 45-59 years old,and 19 cases(9.69%)were 60 years old and above.There was a statistically significant difference in the age of treatment in each group(p<0.05),most of them were young and middle-aged.2 The minimum value of Body Mass Index(BMI)is 28.04kg/m~2,the maximum value is36.57kg/m~2,and the average value(30.20±1.54)kg/m~2.The minimum waist size is 80cm,the maximum value is 112cm,and the average value is(94.63±5.80)cm.Visual Analogue Scale/Score(VAS)minimum value 0,maximum value 7,average value 1.48±2.04.Body surface area(BSA)has a minimum value of 1,a maximum value of 21,and an average value of 7.13±5.38.Dermatology life quality index(DLQI)minimum value 2,maximum value 25,average value 10.02±5.95.The severity of the disease was 40(20.41%)mild,105(53.57%)moderate,and 51(26.02%)severe.There was a difference in the distribution of psoriasis from mild to moderate(P<0.05).Most people male BMI minimum value 28.04kg/m~2,maximum value 36.57kg/m~2,average value(30.26±1.61)kg/m~2,female BMI minimum value 28.04kg/m~2,maximum value 33.33kg/m~2,average value(30.10±1.41)kg/m~2.There was no statistical difference in BMI in terms of gender(p>0.05).The minimum waist circumference for men is85cm,the maximum is 112cm,the average is(95.60±5.63)cm,the minimum waist circumference for women is 80cm,the maximum is 108cm,and the average is(92.87±5.72)cm.According to the spearman correlation test,BMI,waist circumference and VAS,BSA were positively correlated(p<0.05).3 In this study,93 patients(47.45%)reported that they had clear induction or exacerbation factors,31 cases of infection(15.82%),26 cases of diet(13.27%),21 cases of mental factors(10.71%),12 cases of staying up late(6.12%),7 cases of drugs(3.57%),3cases of trauma(1.53%),2 cases of hair dye(1.02%).The composition of the inducing or aggravating factors is different(p<0.05),and the proportion of infectious factors is the highest.4 In this study,86 patients(43.88%)denied the history of other diseases,and 110patients(56.12%)had a history of at least one disease.Among them,38 cases(19.39%)had history of hypertension,9 cases(4.59%)of other cardiovascular diseases;21 cases(10.71%)with hyperlipidemia,17 cases(8.67%)with diabetes,and 12 cases(6.12%)with pharyngitis or tonsillitis,9 cases of liver disease(4.59%),7 cases of kidney disease(3.57%),6 cases of gastrointestinal disease(3.06%),11 cases of autoimmune disease(5.61%),including 1 case of ankylosing spondylitis,1 case of rheumatoid arthritis,2 cases of hypothyroidism,1 case of hyperthyroidism,2 cases of scleroderma,4 cases of dermatomyositis;4 cases of tumor(2.04%);8 other cases(4.08%),including dermatitis and eczema 5 Cases(2.55%),3 cases of urticaria(1.53%),2 cases of vitiligo(1.02%).According to the goodness-of-fit test,p<0.05,the difference is statistically significant.In this study,hypertension accounted for the highest proportion,followed by hyperlipidemia,hyperglycemia,pharyngitis or tonsillitis,autoimmune diseases,other heart disease Vascular diseases,liver diseases,others,kidney diseases,gastrointestinal diseases,tumors.5 Laboratory examination results showed that C-reactive protein increased in 24 cases(12.24%),white blood cell count increased in 27 cases(13.78%)and decreased in 4 cases(2.04%);neutrophil count increased in 48 cases(24.49%),15 cases(7.65%)decreased;31cases(15.82%)increased lymphocyte count,36 cases(18.37%)decreased;12 cases(6.12%)increased eosinophil count,13 cases(6.63%)increased platelet,29 cases of abnormal liver function(14.80%),16 cases of abnormal renal function(8.16%),32 cases of elevated blood lipid(16.33%),21 cases of elevated fasting blood glucose(10.71%),24 cases of abnormal urine(12.24%).6 There were 97 cases(49.49%)in the progress period,68 cases(34.69%)in the resting period,and 31 cases(15.82%)in the regression period.There were statistically significant differences in the stage of the disease course(p<0.05),and the majority of the progress period.81 cases(41.33%)of the internal syndrome of blood heat,15 cases(7.65%)of the syndrome of blood deficiency and wind dryness,43 cases(21.94%)of the syndrome of qi and blood stasis,57 cases(29.08%)of the accumulation of dampness and poison There were statistical differences between the types(p<0.05),and the most evidence of blood heat was intrinsic.Both the internal syndrome of blood heat and the accumulation of dampness and toxin are mainly in the progressive stage,the syndrome of blood deficiency and wind dryness is mainly in the regression period,and the syndrome of qi and blood stasis is mainly in the resting period(p<0.05).The 18-44-year-old and 45-59-year-old age groups mainly consisted of blood-heat internal syndromes,followed by damp-toxin accumulation syndromes.The distribution of the syndrome types of the above age groups was tested and all were p<0.05,the difference was statistically significant.In the age group of 60 years and above,the syndrome of qi and blood stasis is the main one,followed by the accumulation of dampness and toxin.This age group has been tested,P>0.05,the difference is not statistically significant.7 According to the analysis of single physical treatment,there were 13 cases of yin deficiency(6.63%),26 cases of yang deficiency(13.27%),14 cases of qi deficiency(7.14%),16 cases of damp heat(8.16%),and 56 cases of phlegm and dampness(28.57%),41 cases with blood stasis(20.92%),12 cases with qi stagnation(6.12%),8 cases with special quality(4.08%),10 cases with mild quality(5.10%).There are differences between physical types(p<0.05).Phlegm and dampness are the most,followed by blood stasis,yang deficiency,dampness and heat,qi deficiency,yin deficiency,qi stagnation,peace and quality.There are gender differences in various constitution types(p<0.05).Men mainly have phlegm and dampness,blood stasis and yang deficiency,while women have mainly stasis and phlegm.Qi-deficiency and phlegm-dampness were the most common at 18-44 years old,and blood stasis and yang-deficiency were the most common at 45-59 years old.After testing,all were p<0.05,and the difference in age distribution was statistically significant.Qi deficiency,phlegm and dampness,and special qualities were most distributed in 10-15 years,and blood stasis quality was most distributed in 5-10 years.After testing,they were all p<0.05,and the difference in disease course distribution was statistically significant.Yin deficiency quality,Yang deficiency quality,Qi deficiency quality,and specialty quality are mainly based on the syndrome of blood-heat insufficiency,peace quality is mainly based on blood deficiency and wind-dryness syndrome,and blood stasis and qi stagnation are mainly based on qi and blood stasis syndrome,phlegm The wet and damp heat quality is mainly based on wet poison accumulation certificate.After examination,Yin deficiency quality,Yang deficiency quality,Qi deficiency quality,blood stasis quality,phlegm and dampness quality were all p<0.05,and the difference in syndrome distribution was statistically significant;p>0.05,there is no statistically significant difference in syndrome distribution.Conclusion1 BMI,waist circumference were positively correlated with VAS,BSA.2 The syndrome of blood-heat accumulation is the most,followed by the syndrome of damp-toxin accumulation,the syndrome of qi and blood stasis,and the syndrome of blood deficiency and wind-dryness is the least.3 There are differences in physique types.Men mainly rely on phlegm and dampness,while women mainly rely on blood stasis.4 Among the associated diseases,hypertension has the highest proportion,followed by hyperlipidemia,hyperglycemia,pharyngitis or tonsillitis,autoimmune diseases,other cardiovascular diseases,liver diseases,other,kidney diseases,gastrointestinal diseases,tumors.5 There are differences in the composition of induced or aggravated factors,with the highest proportion of infection factors,followed by diet,mental factors,staying up late,drugs,trauma,and hair coloring. |
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