Analysis Of Risk Factors For Type2 Diabetes Foot Amputation

Objective:To analyze the related risk factors of amputation in type 2 diabetes mellitus and provide reference for clinical diagnosis and treatment.Methods:A total of 245 patients with type 2 diabetic foot who were hospitalized in our hospital from January 1,2016 to May 31,2019 were selected.The amputation group was divided into the amputation group(n=86)and the non-amputation group(n=159).General information of all patients was collected: gender,age,occupation,place of residence,education,course of disease,Wanger classification,etc.D-dimer,albumin,HIGH-density lipoprotein,C-reactive protein,fibrinogen,hemoglobin,triglyceride levels,low-density lipoprotein,procalcitonin,and lower extremity vascular color doppler ultrasound were recorded in each group.To observe the incidence of limb infection,amputation and ulcer.To analyze the risk factors of amputation of diabetic foot.Results:In the amputation group,there were 53 males and 33 females with an average age of(58.0±10.3)years.In the non-amputation group,there were 95 males and 64 females with an average age of(61.0±8.2)years.1.There were no significant differences between the amputation group and the non-amputation group in terms of gender,diabetes course and previous medical history;There were statistically significant differences in age,residence and education(P<0.05).2.The proportion of Wagner at or above grade 3 in the amputation group was 87.2%,while that of Wagner at or above grade 3 in the non-amputation group was 33.33%.Wagner's classification of risk was significantly higher in the amputation group than in the non-amputation group.3.There were statistically significant differences in total protein,serum albumin,HIGH-density lipoprotein cholesterol,low-density lipoprotein cholesterol,calcitonin,C-reactive protein,fibrinogen,D-dimer,total cholesterol,and triacylglycerol between the amputation and non-amputation groups(P <0.001).4.Logistic regression analysis showed that triglycerides(OR=10.323,P=0.023),high-density lipoprotein cholesterol(OR=3.171,P=0.034),low-density lipoprotein cholesterol(OR=43.130,P<0.001),C-reactive protein(OR=1.060,P=0.034),albumin(OR=0.750,P=0.012)and D-dimer(OR=1.376,P<0.001)were closely related to amputation in diabetic foot patients.Conclusion:1.Age,residence and education of diabetic foot patients are influencing factors for amputation of diabetic foot patients.2.The longer the course of diabetic foot,the higher the Wanger grade,which is a serious factor affecting the amputation of diabetic foot.3.Combination of triglycerides,HDL cholesterol,LDL cholesterol,C-reactive protein,albumin and D-dimer is a risk factor for diabetic foot amputation.