A Meta-analysis Comparing Femtosecond Laser-assisted Cataract Phacoemulsification With Conventional Phacoemulsification Cataract Surgery

TOPIC:The purpose of this article is to evaluate the efficacy and complications of femtosecond laser-assisted cataract phacoemulsification with meta and compare it with conventional phacoemulsification cataract surgery?METHODS:The domestic and foreign databases were searched,including the following databases: Pubmed,The Cochrane Library,EMBASE,CNKI,Wanfang Database.The literatures from January 2016 to January 2020 were selected.The literatures that met the selection criteria were evaluated by two evaluators independently according to the Cochrane Bias Risk Assessment Tool.According to the "MINORS" standard,non-RCT studies were evaluated and the quality of the included studies was cross-checked.Rev Man5.2.6 software was used for meta-analysis.RESULTS:Nine articles were included in meta-analysis.the results showed that the capsular centering rate of femtosecond laser-assisted cataract phacoemulsification and traditional cataract phacoemulsification(OR=8.01,95% confidence interval:[2.34,27.43:).P=0.0009]),postoperative corneal endothelial cell count(mean difference=117.87,confidence interval: [30.55,205.18,p=0.008]),total breast hyperstimulation time(mean difference =-7.74,confidence interval: [-14.54,0.94,p=0.03]),cumulative dissipated energy(mean difference =-4.37,confidence interval:[-7.98,0.76,p=0.02])have statistically significant differences.However,in the femtosecond laser group,the postoperative uncorrected visual acuity(I2=68%,p=0.64)was observed.The postoperative corrected visual acuity(I2=62%,p=0.98)and central corneal thickness(I2=0%,p=0.88)were not significantly different from those in the traditional cataract group.CONCLUSION:Compared with traditional cataract phacoemulsification,femtosecond laser-assisted cataract phacoemulsification has better effects in reducing corneal endothelial cell loss,improving local neutrality of lens capsule,reducing intraoperative phacoemulsification time and energy,and reducing complications.