Study On The Risk Factors For Fever After Endoscopic Submucosal Dissection Of Gastric Lesions

Objective:Fever is one of the postoperative complications of endoscopic submucosal dissection,but the exact probability and risk factors of postoperative fever are still unclear.The purpose of this study is to investigate the incidence of fever and related risk factors after endoscopic submucosal dissection of gastric lesions,so as to reduce the postoperative fever rate by optimizing preoperative risk assessment and strengthening intraoperative and postoperative management.Methods:We conducted a retrospective study of 1955 patients resected by ESD between January 2014 and January 2019.The included cases were divided into fever group and non-fever group.Statistical analysis included age,sex,previous medical history,lesion location,lesion size,pathology,intraoperative hemorrhage and perforation,operation time,postoperative fever,fever duration and other related factors.Results:Post-ESD fever developed in 451 patients(23.1 %).The highest fever temperature was(37.6±3.12)?,fever days was(1.48±0.85)and 379(84%)patients developed fever 24 hours after operation.Through single factor and multiple factor analysis,age(OR: 1.261,95%CI: 1.009-1.576,p < 0.05),operation duration(OR: 1.457,95%CI: 1.053-2.016,P < 0.05),postoperative gastric tube placement(OR: 2.098,95%CI: 1:616-2.723,p < 0.05),intraoperative hemorrhage(OR: 1.537,95%CI: 1.196-1.974,p < 0.05)and perforation(OR: 1.970,95%CI: 1.531-2.535,p < 0.05)are the relevant risk factors for postoperative fever.Conclusion:Age ?56 years old,operation time ?60min,gastric tube placement,intraoperative hemorrhage and perforation are risk factors for postoperative fever of gastric ESD.Attention should be paid to such patients to minimize the risk of postoperative fever.