Research On Wearable Sensors Based On Prussian Blue Materials

The wearable smart detection of biomarkers in the human body is of great significance in practical fields.Real-time,rapid detection of biomarkers enables early assessment of human health status to avoid diseases.Hydrogen peroxide?H₂O₂?is the product of some enzyme-catalyzed biomolecular reactions.The detection of H₂O₂ can reflect the concentration information of the enzyme reaction biomolecule substrate such as glucose.Therefore,it is of practical value to develop a simple,efficient and low-cost method to detect H₂O₂,and then analyze biomarkers such as glucose.Due to the excellent H₂O₂ sensing performance of Prussian blue?PB?materials,we have developed two PB-based wearable sensors for the successful construction of biosensing devices.In this dissertation,a high-performance Berlin Green carbon ink?BGC ink?for monitoring H₂O₂ was successfully prepared with the help of Prussian blue nanocrystal denoted as Berlin Green?BG?.Wearable smartsensors were developed for detecting H₂O₂ and glucose based on one-step fabricated BG arrays by screen-printing technology.These sensors are wearable,movable and flexible,and exhibited good sensitivity,specificity,stability and reproducibility towards H₂O₂ and glucose detection.In addition,the wearable sensors could be easily remotely and accurately controlled by a smart phone and analyze the target analytes,when integrated with wireless into the device.In this dissertation,PB and reduced graphene oxide?RGO?with excellent electrical properties were combined by oil-water interface self-assembly to successfully prepare a PB/RGO film.PB/RGO film can be supported on a variety of substrates.This paper use carbon cloth as the substrate and develops wearable H₂O₂ and glucose sensors.Both carbon cloth-based wearable H₂O₂ sensors and glucose sensors have excellent sensing performance.They can be easily integrated into textiles and with strong application potential.This article provides a simple,efficient,and low-cost method to develop wearable enzyme-based biosensors based on Prussian blue,and takes glucose sensor as an example to verify the feasibility of biosensor construction,which provides effective means for monitoring biomarkers.In the era of rapid development of the Internet of Things,these biosensors have high development potential in the process of personalized medicine achieving.