| Objective: To examine the role of continuous positive airway pressure(CPAP)in congenital heart disease children combined with cardiac insufficiency and severe pneumonia.Methods: Clinical information of 130 children with congenital heart disease combined with cardiac insufficiency and severe pneumonia were analysed retrospectively.Patients were divided into CPAP group or control group according to therapies.Outcomes including respiratory rate(RR)and heart rate(HR)in 2h,6h and 24 h after treatment,hospitalization days,and left ventricular ejection fraction(EF)after treatment were analysed.Results: No significant difference was found in RR between CPAP and the control group before treatment(64.5±7.9 beats/min vs.62.3±5.9 beats/min,P=0.084);while RR decreased significantly in CPAP group than that in control group(P<0.05).HR was similar between two groups before treatment(157.5±13.9 beats/min vs.158.5±10.6 beats/min,P=0.645);while the HR in CPAP group was remarkably decreased than that in control group after treatment(P<0.05).Cardiac function was monitored dynamicly within 42 cases(17 in CPAP group and 25 in control group)before and after.No difference was found in EF before treatment(66.6±7.7% vs 67.9±6.2%,P=0.550).However,the EF in CPAP group was significantly incraesed than control group after treatment(71.1±5.5% vs 65.9±6.7%,P=0.012).Besides,CPAP group had shorter hospitalization days than control group(8.7±2.2d vs 11.8±3.5d,P=0.000).Conclusion: Conclusion: CPAP can effectively improve the clinical symptoms and reduce hospitalization days of children with congenital heart disease combined with severe pneumonia and cardiac insufficiency;it may also improve the cardiac function. |
