| Objective:Retrospective analysis was performed on 73 patients with elasticfibroma of soft tissue confirmed by pathology during the period from January 2010 to December 2018,and the clinical features of elasticfibroma were summarized,including imaging features,typical pathological features and short-term and long-term surgical effects,so as to provide further clinical diagnosis and treatment experience.Methods:Seventy-three patients with pathologically confirmed soft tissue elastofibroma,from January 2010 to December 2018,were enrolled.The general,clinical,diagnostic,and treatment-related data;operation notes;pathological examination results and follow-up status were obtained by reviewing inpatient medical records.Disease onset age,sex,disease location,and tumour size of elastofibromas were statistically analysed using chi-square and rank-sum tests.Results:A total of 90 lesions from 73 patients were examined.Among these,56 patients had single lesions,located under the right scapula,under the left scapula,at the umbilicus,on the aortic valve,at the right hip,and bilateral inferior angles of the scapula in 27,26,1,1,1,and 17 cases,respectively.Average age at onset was 56.4 years(range:6-82 years).The male-to-female incidence ratio was about 1:3.Tumour diameters and follow-up periods ranged from 2 to 12 cm,and from 1 month to 9 years,respectively;no recurrences were observed.The total incidence of elastofibroma in the datasetanalysed was about 0.04%,and incidences in males and females were about 0.01%and 0.03%,respectively.The incidence in females was 2.84 times higher than that in men.Differences in constituent ratios of the numbers of males and females with the disease had no statistical significance according to the fourfold table ?2 test with?=0.05(?2=0.029,P>0.05).In addition,the data showed that the constituent ratios of single and bilateral disease of elastofibroma dorsi were 76% and 24%,respectively.Lesions in the hips,umbilicus,and aorta were not included in the analysis.Unilateral elastofibroma dorsi was more common,and differences in the constituent ratios of unilateral and bilateral disease had statistical significance according to the fourfold table ?2 test with ?=0.05(?2=4.136,P<0.05).Furthermore,the data from this group showed that the left and right lesions were often of different sizes,and the average volume(mean ± standard deviation)of right lesions was about 143.24±147.80 cm3,the average volume of the left lesions was about 121.59±116.95 cm3.The main symptoms in most patients included pain,swelling,and significant tissue enlargement in a short period of time.Physical examination showed 59 cases of palpable skin masses under the scapulae;37 cases showed significant growth in a short period of time,4 had limited upper limb movement on the affected side,26 had tenderness,and14 had no significant symptoms.All 90 elastofibroma lesions in this group were completely excised by surgery.The follow-up period ranged from 1 month to 9 years,and no recurrence was observed.Short-and long-term outcomes of local excision are good,with no further recurrence.Conclusions:Elastofibroma is a rare benign soft tissue tumour and is common in elderly female patients.The inferior angles of scapulae are the main site of disease,with some cases presenting with bilateral symmetrical disease.Generally,the right lesion is slightly larger than the left lesion.Although elastofibroma can occur in other parts outside the subscapular region,if the lesion is located under the bilateral subscapular region,andthe imaging findings and histological features are typical,it can be diagnosed as elastofibroma without puncture biopsy before operation,and the short-term and long-term outcomes following surgical treatment are good.The study findings can be applied for developing standardised approaches for pathological examinations and imaging studies,to ensure timely and appropriate diagnosis of elastofibroma. |
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