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Application Of The Dose Optimization Technique On 256-slice ICT In Infants And Young Children With Comoplicated Congenital Heart Disease

Posted on:2020-08-26Degree:MasterType:Thesis
Country:ChinaCandidate:Y F ZhouFull Text:PDF
GTID:2404330623457915Subject:Medical imaging and nuclear medicine
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Objective:Investigating the effect of 256-layer iCT dose optimization technique in infants with complex congenital heart disease.Methods:A total of 56 children with congenital heart disease diagnosed from March2015 to September 2018 were enrolled in the study.They were randomly divided into two groups.The control group used the routine 256-slice iCT for retrospective ECG-gated control.While,the experiment group used a 256-slice iCT prospective ECG-gated dose optimization technique.The accuracy,effectiveness,and consistent rate of the images from the two groups in detecting the complex congenital heart disease were analyzed.The radiological quality of images of the two groups was compared using both objective and subjective measures.Results:Analysis of the subjective rating of radiological quality revealed that the proportion of good images was 96.42% and 92.86% in the experiment group and control group,respectively.The difference did not reach statistical significance(P > 0.05).On objective imaging evaluation indexes,the experiment group outperformed the control group slightly on the CT values and the signal-to-noise ratio(SNR)values of the ascending aorta,pulmonary artery trunk,descending aorta,and the left ventricular contrast images.However,the difference failed to reach statistical significance level(P>0.05).The volumetric CT measurement index(CTDI)and dose length product of the study group The(DLP)and effective dose(ED)values ? ? were lower than the conventional group,and the difference between the two groups was statistically significant(t=2.234,P=0.030).T = 3.510,P = 0.001;T =3.194,P=0.002).Conclusion:For the detection of complex congenital heart disease in infants and young children,the application of 256-layer iCT dose optimization technology can not onlyprovide doctors with higher resolution imaging images but also reduce the X-ray doses received by children.It is of great significance for accurate preoperative assessment of complex congenital heart disease in infants and young children.Objective: Investigating the effect of 256-layer iCT dose optimization technique in detecting complex congenital heart disease in infants.Methods:A total of 56 children with congenital heart disease diagnosed from March2015 to September 2018 were enrolled in the study.They were randomly divided into two groups.The control group used the routine 256-slice iCT for retrospective ECG-gated control.While,the experiment group used a 256-slice iCT prospective ECG-gated dose optimization technique.The accuracy,effectiveness,and consistent rate of the images from the two groups in detecting the complex congenital heart disease were analyzed.The radiological quality of images of the two groups was compared using both objective and subjective measures.The validity of preoperative CTA and echocardiography(UCG)was compared in terms of percent of agreement with surgical results,which served as the golden standard.Results:A total of 24 types of cardiovascular malformations were found in the two groups,which included 5 types of congenital intra-cardiac structural abnormalities and19 types of congenital macrovascular malformations.According to the surgical results,there were 5 missed diagnoses in the experiment group,and 7 missed diagnoses in the control group.The control group was slightly higher than the experiment group,and the difference was not statistically significant(P>0.05).In terms of percent of agreement with surgical results,the rate of extra-cardiac structural abnormalities in the study group and control group was 99.74% and 99.59%,respectively.The study group was slightly higher than the conventional group(P>0.05).The coincidence rate of intra-and extra-cardiac structural abnormalities in the study group was 99.26% and 99.55%,respectively.While,in the control group,the coincidence rate was 99.11% for both intra-and extra-cardiac structural abnormalities.The difference between the two groups was not statistically significant(P>0.05).The detection rate of extracardiac,intracardiac structural abnormalities,and extra-temporal abnormalities in the experiment group was96.08%,93.94%,92.33%,respectively.In the control group,the detection rate was92.69%,93.11%,and 93.33%,respectively.There was no significant difference in the detection rate between the two groups(P>0.05).The preoperative rate of total CTA diagnosis in the two groups(94.2%)was better than that of UCG(88.5%).The difference between the two methods was statistically significant(?2=4.379,P=0.036).Conclusion:The application of 256-layer iCT dose optimization technique to detect cardiac malformations in infants with complex congenital heart disease can reduce the incidence of adverse reactions caused by X-rays,and clearly show abnormal anatomical structures,which can significantly reduce the incidence of misdiagnosis.It is of great significance to determine the degree of cardiac malformation in infants with complex congenital heart disease.
Keywords/Search Tags:iCT, dose optimization technique, infants, complex congenital heart disease, image quality, cardiac malformation
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