Comparative Analysis Of The Effectiveness Of Standard Radical Surgery And Expanded Radical Surgery For Pancreatic Cancer

Objective:Comparative analysis of pancreatic cancer standard radical treatment and expand the radical ??? period clinical effect of pancreatic cancer.Methods:134 cases of pancreatic cancer patients admitted to Jinqiu hospital from January 2011 to December 2016 were selected as observation objects.The patients were divided into two groups according to the surgical methods adopted,the control group(standard radical surgery for pancreatic cancer)had 61 cases,and the observation group(extended radical surgery for pancreatic cancer)had 73 cases.The rate of tumor resection rate,pain relief,the incidence and happening time of postoperative complications,and postoperative survival time were compared between two groups.Results:In the control group,55 cases were completely resected and 6 cases were not completely resected,with a tumor resection rate of 90.16%.The tumor resection rate was 93.15%in the observation group of 68 cases of complete tumor resection and 5 cases of incomplete tumor resection with extended radical resection of pancreatic cancer,and the difference in tumor resection rate between the two groups was not statistically significant(?2=0.393,P>0.05).In the control group,there were 51 cases of pain relief and 10 cases without pain relief,and the rate of pain relief was 83.61%.There were 62 cases of pain relief and 11 cases without pain relief in the observation group,and the rate of pain relief was 84.93%.There was no significant difference in the rate of pain relief between the two groups(?2=0.044,P>0.05).The incidence of delayed gastric emptying(1.47%vs.10.96%),pancreatic fistula(1.47%vs.13.70%)and biliary fistula(3.28%vs.10.96%)in the control group was lower than that in the observation group,and the difference was statistically significant(P<0.05).Cholangitis(4.92%vs.5.48%),abdominal abscess(9.84%vs.6.85%),abdominal hemorrhage(6.56%vs.2.74%),incision infection(6.56%vs.8.22%),gastrointestinal fistula(8.20%vs.6.85%),diarrhea(3.28%vs.6.85%),intestinal obstruction(9.84%vs.2.74%),pneumonia(1.47%vs.2.74%),and secondary surgery(11.48%vs.12.33%).There was no significant difference in incidence(P>0.05).There was no significant difference in 1-year survival rate(88.52%vs.86.30%)between the two groups(P>0.05).The 2-year survival rate(62.30%vs.78.80%)and 3-year survival rate(44.26%vs 61.64%)in the control group were lower than those in the observation group,and the differences were statistically significant(P<0.05).Survival time of patients with positive lymph node metastasis between the two groups was statistically significant[(21.4 vs.3.2)months vs.(18.3 vs.2.7)months,P<0.05].While there was no significant difference in survival time[(22.4 vs.3.5)months vs.(23.1 vs.3.9)months,P>0.051 between two groups of patients with negative lymph node metastasis.Conclusions:standard radical treatment and expand the radical ??? period in tumor resection of pancreatic cancer,little difference between the symptom control;However,the delayed gastric emptying,pancreatic fistula and complications of pancreatic fistula were not as good as the standard radical resection.For survival,extended radical resection has some advantages in the long-term survival and lymph node metastasis positive patient population.Therefore,the treatment of pancreatic cancer should be based on the patient s own characteristics of the surgical method,should not blindly pursue a wide range of surgical resection.